VivoSeq
Other

Acanthosis Nigricans

5

Pipeline Programs↗

0

Active Trials↗

5

Companies Involved↗

Acanthosis Nigricans is an early-stage landscape with 5 programs across 5 companies. The most active players are Pfizer, Eastern Cooperative Oncology Group, Aucta Pharmaceuticals, Inc. 2 therapies are approved.

Intelligence

Pipeline Metrics

Competitive Density

27/100

Pipeline Velocity

0/100

Mech. Concentration

25/100

Completion Rate

100/100

Attrition Rate

0/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Pfizer logo

Pfizer

1 program

Phase 2E

Eastern Cooperative Oncology Group

1 program

Phase 2A

Aucta Pharmaceuticals, Inc

1 program

Phase 2EMD Serono logo

EMD Serono

1 program

ApprovedP

Prism Pharmaceuticals

1 program

Approved

Pipeline

Programs by Phase

Analysis

Trial Status

7

clinical trials

Completed6 · 86%
Unknown status1 · 14%

Clinical Trials

Trial Activity

7 trials

The Efficacy Tretinoin Cream in the Treatment of Axillary Hyperpigmentation Associated With Acanthosis Nigricans
Completed·SSrinakharinwirot University·Phase 3·NCT06213987·20 enrolled
Comparison Of Outcome Of Treatment OF Topical 15%TCA VS Topical 0.05% Tretinoin In Treatment Of Acanthosis Nigricans
Completed·JJinnah Postgraduate Medical Centre·N/A·NCT06008327·80 enrolled
Evaluating the Safety and Efficacy of Topical Sirolimus 0.2% to Treat Acanthosis Nigricans
Completed·NNarrows Institute for Biomedical Research·Phase 2·NCT06940895·5 enrolled
Efficacy of Chromium Picolinate in Reducing Acanthosis Nigricans Severity in Adolescents With Insulin Resistance
Completed·UUruk University·N/A·NCT07371169·90 enrolled
Spectroscopic and Colorimetric Analysis of Acanthosis Nigricans in Patients With Hyperinsulinemia
Completed·HHenry Ford Health System·N/A·NCT01125150·9 enrolled
Phase II Study of the Effect of Leuprolide Acetate and Spironolactone on Insulin Resistance in Hyperandrogenic Women With Polycystic Ovarian Disease or Hyperandrogenism Insulin Resistance Acanthosis Nigricans Syndrome
Completed·NNational Center for Research Resources (NCRR)·Phase 2·NCT00004311
Study of Efficacy of Metformin in the Treatment of Acanthosis Nigricans in Children With Obesity
Unknown status·—·Phase 4·NCT02438020·30 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)