VivoSeq
Other

Aggressive Periodontitis

10

Pipeline Programs↗

0

Active Trials↗

3

Companies Involved↗

Aggressive Periodontitis is an early-stage landscape with 10 programs across 3 companies. The most active players are Pfizer's Upjohn has merged with Mylan to form Viatris Inc., Bayer, AbbVie. 3 therapies are approved with 3 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

36/100

Pipeline Velocity

0/100

Mech. Concentration

25/100

Completion Rate

100/100

Attrition Rate

0/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

P

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

1 program

Phase 1Bayer logo

Bayer

1 program

Phase 3AbbVie logo

AbbVie

1 program

Preclinical

Pipeline

Programs by Phase

Analysis

Trial Status

12

clinical trials

Completed10 · 83%
Unknown status2 · 17%

Clinical Trials

Trial Activity

12 trials

Host Modulatory Effects of β-glucan on Localized Aggressive Periodontitis
Completed·—·Phase 4·NCT02402296·30 enrolled
Triclosan as Adjunctive Therapy in the Plaque Control in Children From Generalized Aggressive Periodontitis Families.
Completed·UUniversity of Campinas, Brazil·Phase 4·NCT03642353·40 enrolled
Omega-3 Fatty Acids Plus Low-dose Aspirin Daily Supplementation in Surgical Therapy to Treat Aggressive Periodontitis
Completed·UUniversidade Estadual Paulista Júlio de Mesquita Filho·Phase 2/3·NCT03093207·34 enrolled
Evaluation of Efficacy of Full-mouth Disinfection in Generalized Aggressive Periodontitis Patients
Completed·MMarmara University·Phase 4·NCT02466646·42 enrolled
Periodontal Debridement Associated With Systemic Antibiotics and Single/Repeated PDT to Treat Aggressive Periodontitis
Completed·UUniversidade Estadual Paulista Júlio de Mesquita Filho·Phase 2/3·NCT03132714·46 enrolled
Omega-3 Plus Low-dose Aspirin Daily Supplementation in Non-surgical Therapy to Treat Aggressive Periodontitis
Completed·UUniversidade Estadual Paulista Júlio de Mesquita Filho·Phase 2/3·NCT03093246·38 enrolled
Two Different Antibiotic Agents to Treat Generalized Aggressive Periodontitis
Completed·UUniversidade Estadual Paulista Júlio de Mesquita Filho·Phase 2/3·NCT02969928·46 enrolled
Amoxicillin and Metronidazole in Association With Non-surgical Therapy in Aggressive Periodontitis Treatment
Completed·UUniversity of Campinas, Brazil·Phase 4·NCT03933501·48 enrolled
Antimicrobial Photodynamic Therapy in Treatment of Aggressive Periodontitis (Stage III, Grade C Periodontitis)
Completed·UUniversity of Ljubljana·N/A·NCT05655338·20 enrolled
Doxycycline in the Treatment of Aggressive Periodontitis
Completed·MMohammed V Souissi University·Phase 1/2·NCT03727620·24 enrolled
Influence of Smoking on Clinical, Microbiological and Immunologic Parameters in Patients With Aggressive Periodontitis.
Unknown status·UUniversity of Campinas, Brazil·N/A·NCT04051255·30 enrolled
Efficacy of Three Antibiotic Protocols for Aggressive Periodontitis Treatment
Unknown status·FFacultad Nacional de Salud Publica·Phase 4·NCT02839421·36 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)