VivoSeq
Other

Alcohol Abuse

24

Pipeline Programs↗

1

Active Trials↗

18

Companies Involved↗

Alcohol Abuse is an emerging landscape with 24 programs across 18 companies. The most active players are Astellas, Novo Nordisk, COMPASS Pathways. 14 therapies are approved with 1 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

48/100

Pipeline Velocity

6/100

Mech. Concentration

10/100

Completion Rate

80/100

Attrition Rate

18/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Astellas logo

Astellas

1 program

Phase 2Novo Nordisk logo

Novo Nordisk

1 program

Phase 2COMPASS Pathways logo

COMPASS Pathways

1 program

Phase 2V

Viatris Specialty LLC

1 program

Phase 2Mylan Pharmaceuticals Inc logo

Mylan Pharmaceuticals Inc

1 program

Phase 2J

Javelin Pharmaceuticals

1 program

Phase 3

Pipeline

Programs by Phase

Analysis

Modality Breakdown

96%

Small molecule

23 of 24 classified programs — the dominant modality here.

4%ALL OTHERSPeptide14%

Small molecule leads; the ring shows all 24 classified programs, each share of the total. Modality classified for 100% of 24 pipeline programs.

Analysis

Trial Status

11

clinical trials

Completed8 · 73%
Withdrawn2 · 18%
Recruiting1 · 9%

Clinical Trials

Trial Activity

11 trials

The Effect of Comorbid Alcohol/Substance Use on Social Inclusion and Clinical Outcome in Individuals With Severe Mental Illness Enrolled in a Community Mental Health Center: A Cross-Sectional Case-Control Study
Recruiting·AAbant Izzet Baysal University·N/A·NCT07692984·297 enrolled
Naltrexone Treatment of Alcohol Abuse in Schizophrenia
Completed·SState University of New York - Upstate Medical University·Phase 4·NCT00145847·90 enrolled
Quetiapine in Patients With Bipolar and Alcohol Abuse/Dependence
Completed·UUniversity of Texas Southwestern Medical Center·Phase 4·NCT00223249·115 enrolled
STAR*D Alcohol: Treatment of Depression Concurrent With Alcohol Abuse
Completed·NNew York State Psychiatric Institute·N/A·NCT00369746·674 enrolled
Disulfiram for Cocaine-Alcohol Abuse - 3
Completed·YYale University·Phase 2·NCT00000278
Atomoxetine Treatment of Adults With ADHD and Comorbid Alcohol Abuse
Completed·Eli Lilly logoEli Lilly·Phase 4·NCT00190957·140 enrolled
Trial of the Rapid Antisuicidal Effects of Intranasal Ketamine in Comorbid Depression and Alcohol Abuse
Completed·TThe University of Texas Health Science Center, Houston·Phase 3·NCT03539887·33 enrolled
Sex Differences in Risk for Alcohol Abuse
Completed·—·N/A·NCT04543942·28 enrolled
Medication Development for Opioid and Alcohol Abuse
Completed·NNew York State Psychiatric Institute·Phase 2·NCT03205423·17 enrolled
Open-Label Depakote ER in Patients With Bipolar I or II Depression and Alcohol Abuse or Dependence
Withdrawn·TThe University of Texas Medical Branch, Galveston·Phase 2·NCT00204503
Contingency Management Using Deposit Contract to Reduce Drinking
Withdrawn·TThe University of Texas Health Science Center at San Antonio·Preclinical·NCT05837611

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)