VivoSeq
Other

Aphasia

15

Pipeline Programs↗

11

Active Trials↗

9

Companies Involved↗

Aphasia is an emerging landscape with 15 programs across 9 companies. The most active players are EIP Pharma Inc, Orion Corporation, Orion Pharma, UCB. 5 therapies are approved with 1 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

46/100

Pipeline Velocity

19/100

Mech. Concentration

29/100

Completion Rate

92/100

Attrition Rate

4/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

E

EIP Pharma Inc

1 program

Phase 2Orion Corporation, Orion Pharma logo

Orion Corporation, Orion Pharma

1 program

Phase 3UCB logo

UCB

2 programs

ApprovedEisai logo

Eisai

1 program

ApprovedAbbVie logo

AbbVie

2 programs

ApprovedM

Merz Pharmaceuticals GmbH

1 program

Preclinical

Pipeline

Programs by Phase

Analysis

Trial Status

26

clinical trials

Completed11 · 42%
Recruiting8 · 31%
Unknown status3 · 12%
Terminated1 · 4%
Not yet recruiting1 · 4%
Enrolling by invitation1 · 4%
Other1 · 4%

Clinical Trials

Trial Activity

26 trials

Escitalopram and Language Intervention for Subacute Aphasia
Recruiting·JJohns Hopkins University·Phase 2·NCT03843463·88 enrolled
Propranolol in Primary Progressive Aphasia
Recruiting·UUniversity of Missouri-Columbia·Phase 1·NCT06066710·30 enrolled
Effects of Cerebrolysin on Language Ability in Non-fluent Aphasia Patients After Stroke: A Randomized, Placebo-controlled, Double-blinded, Single Center Study
Recruiting·YYonsei University·Phase 4·NCT06897176·40 enrolled
Transcranial Direct Current Stimulation to Treat Aphasia: A Superiority Study
Recruiting·UUniversity of South Carolina·Preclinical·NCT07688551·130 enrolled
Exogenous Tuning of Neural Oscillations as a Mode of Treatment in Post-stroke Aphasia
Recruiting·MMedical College of Wisconsin·Preclinical·NCT04375722·50 enrolled
Precision Neuromodulation in Post-Stroke Aphasia Using TMS
Recruiting·MMedical College of Wisconsin·Preclinical·NCT06974279·50 enrolled
Genetic and MRI Biomarkers of Neuroplasticity Predict Aphasia Recovery and Phenotypes
Recruiting·UUniversity of Wisconsin, Madison·Preclinical·NCT06471127·90 enrolled
Comparing the Effectiveness of Traditional Semantic Feature Analysis (SFA) Versus SFA Plus Metacognitive Strategy Training (SFA+MST) for People With Acquired Aphasia
Recruiting·Teachers College, Columbia University·Phase 2·NCT07036406·40 enrolled
Treatment Outcomes and Brain Mechanisms Associated With Non-Invasive Neuromodulation in Post-Stroke Aphasia
Active, not recruiting·UUniversity of Arkansas·Preclinical·NCT03929432·50 enrolled
Word Retrieval in Aphasia
Not yet recruiting·AAlbert Einstein Healthcare Network·Preclinical·NCT07673198·12 enrolled
Word Retrieval in Aphasia
Enrolling by invitation·AAlbert Einstein Healthcare Network·Preclinical·NCT07179458·20 enrolled
Donepezil in Chronic Poststroke Aphasia: a Randomized Controlled Trial
Completed·GGabinete Berthier y Martínez·Phase 4·NCT00196690·30 enrolled
Effect of Dopaminergic Medication on Recovery of Aphasia
Completed·UUniversity Hospital, Geneva·N/A·NCT00941265·12 enrolled
Augmenting Language Therapy for Aphasia: Levodopa
Completed·—·Phase 2/3·NCT01429077·36 enrolled
The Effect of Venlafaxine on Language Function in Patients With Subcortical Aphasia: A fMRI Study
Completed·GGuangzhou General Hospital of Guangzhou Military Command·N/A·NCT03588572·43 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)