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Other/Bone

Bone

12

Pipeline Programs↗

26

Active Trials↗

14

Companies Involved↗

Bone is an emerging landscape with 12 programs across 14 companies.

Intelligence

Pipeline Metrics

Competitive Density

49/100

Pipeline Velocity

41/100

Mech. Concentration

100/100

Completion Rate

90/100

Attrition Rate

6/100

Pipeline

Programs by Phase

Preclinical9

Matched Placebo (capsules)

Creighton University

Elelyso

Shaare Zedek Medical Center

Ertapenem

Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Bone Marrow Aspirate Concentrate

Massachusetts General Hospital

Rhbmp-2 Placement

Aya Adil Saeed

Phase 1

No programs

Phase 23

Transdermal EE+LNG

University of Virginia

I-PRF and FDBA

Krishnadevaraya College of Dental Sciences & Hospital

BOOST Cells

Karolinska Institutet

Phase 3

No programs

Approved

No programs

Analysis

Trial Status

101

clinical trials

Completed56 · 55%

Unknown status13 · 13%

Recruiting10 · 10%

Not yet recruiting7 · 7%

Enrolling by invitation5 · 5%

Active, not recruiting4 · 4%

Other6 · 6%

Clinical Trials

Trial Activity

101 trials

Autologous Bone Marrow Aspirate Concentrate in Patients Undergoing Meniscectomy

Recruiting·RRush University Medical Center·N/A·NCT02582489·100 enrolled

Post-Market Clinical Follow-Up of the Osia System and Evaluation of Benefits of Transitioning From the Baha Connect System to the Osia System in Adult Bone Conduction Implant Recipients With Mixed or Conductive Hearing Loss

Recruiting·CCochlear·Preclinical·NCT07130136·20 enrolled

RELIEVED (REgionaL anesthesIa PElVic fracturEs stuDy) Study. Regional Anesthesia (RA) Techniques for Pain Management in Pelvic Fractures: A Prospective, Monocentric, Pilot Cohort Study. Pain Management in Surgical and Conservative Settings."

Recruiting·AA.O.U. Città della Salute e della Scienza·N/A·NCT07072286·177 enrolled

Radiographic Findings and Clinical Outcomes After Bone Grafting Patellar Defect in ACL Reconstruction

Recruiting·UUniversity of Arizona·Preclinical·NCT06975306·75 enrolled

Evaluation of the Epione Robotic System for Image-guided Percutaneous MSK Procedures of the Pelvis and Spine in USA. A Prospective Study on Feasibility, Safety and Accuracy

Recruiting·PPrecision IO Group·Preclinical·NCT07325578·60 enrolled

Role of Estrogen Formulation and Route of Delivery on Skeletal Outcomes in Functional Hypothalmic Amenorrhea

Recruiting·UUniversity of Virginia·Phase 2·NCT07010146·150 enrolled

Comparison of Flapless Immediate Implant Placement With Titanium Mesh Versus Immediate Implants Placement With Collagen Membrane in Type II Socket: A Randomized Clinical Trial

Recruiting·MMisr International University·Preclinical·NCT06875830·20 enrolled

Precision and Reliability of Dual X-ray Absorptiometry (DXA) Testing

Recruiting·PPenn State University·N/A·NCT03621306·400 enrolled

Effect of Calcium and Vitamin D Supplements and/or Prunes on Bone Health

Recruiting·San Diego State University·Preclinical·NCT06184646·200 enrolled

Contribution of MUltiparametric Analysis in Bone Scintigraphy for the Characterisation of Solitary Bone Lesions Whose Malignant Origin Cannot be Excluded on Conventional Imaging

Recruiting·CCentral Hospital, Nancy, France·Preclinical·NCT05934994·68 enrolled

Resorbable vs Non-resorbable Bone Substitute at Immediate Post-extractive Single Implants

Active, not recruiting·—·Phase 3·NCT07047131·50 enrolled

BMP Effect on Implant Stability and Marginal Bone Level After Immediate Placement

Active, not recruiting·—·N/A·NCT07240493·24 enrolled

Boost Brittle Bones Before Birth

Active, not recruiting·KKarolinska Institutet·Phase 1/2·NCT03706482·18 enrolled

The Effect of High-Dose Vitamin D and Physical Activity on Bone Health in Breast Cancer Patients Receiving Hormonal Therapy

Active, not recruiting·UUniversity of Rochester·Phase 2·NCT01419730·191 enrolled

Clinical Study on the Efficacy of Magnesium-Containing Degradable Polymer Bone Repair Material for Repairing Bone Defects After Extremity Bone Tumor Resection

Not yet recruiting·—·Preclinical·NCT07794202·72 enrolled

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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)