VivoSeq
Psychiatry

Cocaine Abuse

25

Pipeline Programs↗

0

Active Trials↗

13

Companies Involved↗

Cocaine Abuse is an emerging landscape with 25 programs across 13 companies. The most active players are Azurity Pharmaceuticals, Omnivium, Teva. 5 therapies are approved with 2 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

49/100

Pipeline Velocity

0/100

Mech. Concentration

13/100

Completion Rate

97/100

Attrition Rate

3/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

A

Azurity Pharmaceuticals

1 program

Phase 1O

Omnivium

1 program

Phase 2Teva logo

Teva

1 program

Phase 2V

Validus Pharmaceuticals

1 program

Phase 2V

Vitae Pharmaceuticals Inc., an Allergan affiliate

1 program

Phase 2V

Viatris Specialty LLC

1 program

Phase 2

Pipeline

Programs by Phase

Analysis

Trial Status

29

clinical trials

Completed28 · 97%
Terminated1 · 3%

Clinical Trials

Trial Activity

29 trials

Effect of Nefazodone on Relapse in Females With Cocaine Abuse - 10
Completed·National Institute on Drug Abuse (NIDA)·Phase 3·NCT00000293
Effects of Nefazodone on Treatment of Female Cocaine Abusers - 3
Completed·National Institute on Drug Abuse (NIDA)·Phase 2·NCT00000286
Disulfiram for Cocaine Abuse in Buprenorphine Treatment
Completed·YYale University·Phase 2·NCT00913484·177 enrolled
Rapid Evaluation of Amantadine for Treatment of Cocaine Abuse/Dependence - 4
Completed·UUniversity of California, Los Angeles·Phase 2·NCT00000301
Mazindol for Cocaine Abuse - 2
Completed·YYale University·Phase 2·NCT00000277
Pemoline for Cocaine Abuse - 7
Completed·YYale University·Phase 2·NCT00000282
A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine Abuse
Completed·IIndivior Inc.·Phase 2·NCT01846481·40 enrolled
Human Dopamine Transported Imaging in Cocaine Abuse: 1 - 1
Completed·National Institute on Drug Abuse (NIDA)·Phase 1·NCT00000315
Glutaminergic Agents for Cocaine Abuse - 5
Completed·YYale University·Phase 1·NCT00000280
Cocaine Abuse and Attention Deficit Disorder - 3
Completed·National Institute on Drug Abuse (NIDA)·N/A·NCT00000268·32 enrolled
Human Dopamine Transported Imaging in Cocaine Abuse: 2 - 2
Completed·National Institute on Drug Abuse (NIDA)·Phase 1·NCT00000316
Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse
Completed·VVA Office of Research and Development·Phase 2·NCT01953432·43 enrolled
Flupenthixol and Haloperidol for Treating Cocaine Abuse Schizophrenics - 9
Completed·National Institute on Drug Abuse (NIDA)·Phase 2·NCT00000274·60 enrolled
Rapid Evaluation of Baclofen for Treatment of Cocaine Abuse/Dependence - 6
Completed·UUniversity of California, Los Angeles·Phase 2·NCT00000303
Clinical Efficacy of Disulfiram in LAAM-Maintained Cocaine Abusers
Completed·YYale University·N/A·NCT00580827·126 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)