VivoSeq
Other

Colchicine

1

Pipeline Programs↗

7

Active Trials↗

4

Companies Involved↗

Colchicine is an early-stage landscape with 1 program across 4 companies. The most active players are Alnylam Pharmaceuticals, Eli Lilly, Mutual Pharmaceutical Company, Inc.. 1 therapy is approved.

Intelligence

Pipeline Metrics

Competitive Density

25/100

Pipeline Velocity

15/100

Mech. Concentration

100/100

Completion Rate

79/100

Attrition Rate

13/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Alnylam Pharmaceuticals logo

Alnylam Pharmaceuticals

1 program

ApprovedEli Lilly logo

Eli Lilly

1 program

ApprovedM

Mutual Pharmaceutical Company, Inc.

0 programs

PreclinicalNovartis logo

Novartis

0 programs

Preclinical

Pipeline

Programs by Phase

Preclinical
No programs
Phase 1
No programs
Phase 2
No programs
Phase 3
No programs
Approved1

Colchicine

Alnylam Pharmaceuticals

Analysis

Trial Status

31

clinical trials

Completed15 · 48%
Recruiting6 · 19%
Unknown status5 · 16%
Terminated4 · 13%
Not yet recruiting1 · 3%

Clinical Trials

Trial Activity

31 trials

The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial
Recruiting·VVA Office of Research and Development·Phase 4·NCT05618353·700 enrolled
Colchicine in Acutely Decompensated HFREF
Recruiting·UUniversity of Virginia·Phase 4·NCT06286423·30 enrolled
Colchicine Use in Intracranial Atherosclerotic Disease
Recruiting·—·Phase 2·NCT05503225·72 enrolled
The Effect of ColcHicine on the Incidence of Knee or Hip Replacements
Recruiting·—·Phase 3·NCT06578182·1,410 enrolled
Precision Colchicine Intervention to Suppress Atherosclerosis in TET2 Clonal Hematopoiesis : a Pilot Clinical Trial (PRECISE)
Recruiting·SShenyang Northern Hospital·Approved·NCT07362966·120 enrolled
Adjunctive Colchicine's Effect on Inflammatory Markers and Corresponding New-Onset Atrial Fibrillation Rates Post Coronary Artery Bypass Graft Procedure: A Pilot Study
Recruiting·—·Approved·NCT07287345·24 enrolled
Perioperative Colchicine for TKA
Not yet recruiting·GGeisinger Clinic·Phase 4·NCT06936709·75 enrolled
Oral Colchicine in Argentina to Prevent Restenosis
Completed·CCentro de estudios en Cardiologia Intervencionista·Phase 4·NCT04382443·410 enrolled
Colchicine Or Naproxen Treatment for ACute gouT
Completed·KKeele University·Phase 4·NCT01994226·399 enrolled
Anti-platelet Effects of Colchicine in Healthy Volunteers
Completed·NNYU Langone Health·Phase 4·NCT02140372·10 enrolled
Bioequivalence Study of Colchicine Tablets
Completed·MMutual Pharmaceutical Company, Inc.·Phase 1·NCT01021020·28 enrolled
Pharmacokinetic Study With Colchicine in Healthy Volunteers
Completed·MMutual Pharmaceutical Company, Inc.·Phase 1·NCT01017003·14 enrolled
Study of Long-term Peg Intron vs. Colchicine in Non-responders.
Completed·—·Phase 4·NCT00179413·549 enrolled
A Pharmacokinetic Study of Colchicine With an Oral Contraceptive
Completed·MMutual Pharmaceutical Company, Inc.·Phase 1·NCT01040845·30 enrolled
Adjuvant Use Of Colchicine With The Standard Therapy In Moderate And Severe Corona Virus Disease-19 Infection
Completed·UUniversity of Baghdad·Phase 1·NCT05151614·160 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)