VivoSeq
Other

Cough

21

Pipeline Programs↗

4

Active Trials↗

14

Companies Involved↗

Cough is an emerging landscape with 21 programs across 14 companies. The most active players are GSK, Pfizer's Upjohn has merged with Mylan to form Viatris Inc., Chattem. 16 therapies are approved.

Intelligence

Pipeline Metrics

Competitive Density

48/100

Pipeline Velocity

15/100

Mech. Concentration

11/100

Completion Rate

89/100

Attrition Rate

7/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

GSK logo

GSK

1 program

Phase 1P

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

2 programs

ApprovedC

Chattem

1 program

ApprovedA

Averitas Pharma, Inc.

1 program

ApprovedK

Kenvue Brands

1 program

ApprovedM

McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

1 program

Approved

Pipeline

Programs by Phase

Analysis

Trial Status

15

clinical trials

Completed8 · 53%
Unknown status2 · 13%
Not yet recruiting2 · 13%
Withdrawn1 · 7%
Recruiting1 · 7%
Active, not recruiting1 · 7%

Clinical Trials

Trial Activity

15 trials

The Safety, Feasibility, and Repeatability of Inhaled ATP Cough Challenges
Recruiting·MMcMaster University·Phase 1·NCT07085975·33 enrolled
Influence on Cough and Airway Symptoms by Oral Capsaicin
Active, not recruiting·—·Phase 2·NCT04125563·60 enrolled
A Phase 1 Study to Evaluate the PK and Relative Bioavailability of Different Formulation Prototypes of Camlipixant
Not yet recruiting·GSK logoGSK·Phase 1·NCT07684586·28 enrolled
Oliceridine vs Sufentanil for Cough During General Anesthesia Induction: A Randomized Controlled Trial
Not yet recruiting·—·Approved·NCT07660380·62 enrolled
BENEFITS OF ACLIDINIUM BROMIDE IN THE RELIEF OF COPD SYMPTOMS INCLUDING COUGH
Completed·AstraZeneca logoAstraZeneca·Phase 4·NCT02375724·300 enrolled
Cough According to Stimulus Type in PD
Completed·UUniversity of Florida·Phase 1·NCT02390089·158 enrolled
Warming Sensation and Tolerability Study of Acetylcysteine 2% Oral Solution for Productive Cough
Completed·GSK logoGSK·Phase 3·NCT02822287·58 enrolled
Evaluating the Effect of Mucinex® 1200 mg on Mucociliary and Cough Clearance From the Human Lung
Completed·UUniversity of North Carolina, Chapel Hill·Phase 1·NCT00902707·12 enrolled
Comparison of SCH 486757 to Codeine and Placebo in Subjects With Persistent Postviral Cough (Study P03069AM2)(COMPLETED)
Completed·Merck & Co. logoMerck & Co.·Phase 2·NCT00230230·91 enrolled
The Effects of Salbutamol on Mannitol Induced Cough Responses in Healthy Controls
Completed·MMcMaster University·Phase 2·NCT04565847·20 enrolled
Clinical Response of Syrup Hydryllin® in Pakistani Subjects With Cough in Routine Practice
Completed·TThe Searle Company Limited Pakistan·N/A·NCT05129761·320 enrolled
Effect of Gefapixant (AF-219/MK-7264) on Cough Reflex Sensitivity (MK-7264-015)
Completed·Merck & Co. logoMerck & Co.·Phase 2·NCT02397460·50 enrolled
Pulmozyme for Sjogren's Associated Cough
Withdrawn·UUConn Health·Phase 1·NCT01357447
Dezoxide Suppresses Sufentanil-induced Cough
Unknown status·SShanghai Zhongshan Hospital·N/A·NCT05532449·176 enrolled
Effect of Oral Procaterol on Postinfectious Persistent Cough
Unknown status·MMahidol University·N/A·NCT02349919·74 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)