VivoSeq
Oncology

Dedifferentiated Liposarcoma

21

Pipeline Programs

6

Active Trials

14

Companies Involved

Dedifferentiated Liposarcoma is an emerging landscape with 21 programs across 14 companies. The most active players are Incyte, Bristol-Myers Squibb, Novartis. 1 therapy is approved with 5 more in late-stage development.

Pipeline Metrics

Competitive Density

48/100

Pipeline Velocity

0/100

Mech. Concentration

14/100

Completion Rate

38/100

Attrition Rate

31/100

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Programs by Phase

Modality Breakdown

76%

Small molecule

16 of 21 classified programs — the dominant modality here.

24%ALL OTHERSMonoclonal antibody524%

Small molecule leads; the ring shows all 21 classified programs, each share of the total. Modality classified for 100% of 21 pipeline programs.

Trial Status

16

clinical trials

Active, not recruiting5 · 31%
Terminated4 · 25%
Completed3 · 19%
Unknown status2 · 13%
Recruiting1 · 6%
Withdrawn1 · 6%

Trial Activity

16 trials

Study of Abemaciclib in Dedifferentiated Liposarcoma
Active, not recruiting·MMemorial Sloan Kettering Cancer Center·Phase 2·NCT02846987·33 enrolled
ATX-101 in Advanced Dedifferentiated Liposarcoma and Leiomyosarcoma
Terminated··Phase 2·NCT05116683·4 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)