VivoSeq
Cardiovascular

Diastolic Dysfunction

1

Pipeline Programs↗

0

Active Trials↗

1

Companies Involved↗

Diastolic Dysfunction is an early-stage landscape with 1 program across 1 company. The most active players are Eastern Cooperative Oncology Group.

Intelligence

Pipeline Metrics

Competitive Density

10/100

Pipeline Velocity

0/100

Mech. Concentration

N/A

Completion Rate

57/100

Attrition Rate

38/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

E

Eastern Cooperative Oncology Group

1 program

Preclinical

Pipeline

Programs by Phase

Preclinical1

Sulforaphane

Eastern Cooperative Oncology Group

Phase 1
No programs
Phase 2
No programs
Phase 3
No programs
Approved
No programs

Analysis

Trial Status

8

clinical trials

Completed4 · 50%
Terminated2 · 25%
Unknown status1 · 13%
Withdrawn1 · 13%

Clinical Trials

Trial Activity

8 trials

Simvastatin and Diastolic Dysfunction
Completed·BBrasilia Heart Study Group·Phase 4·NCT01061450·55 enrolled
Echocardiographic Evaluation of the Effects of Dexmedetomidine in Diastolic Dysfunction
Completed·YYonsei University·N/A·NCT02490072·40 enrolled
Early Diagnosis of Diastolic Dysfunction and Reliability of DSE in Detecting Stress Diastolic Dysfunction
Completed·UUniversity of Missouri-Columbia·N/A·NCT00998205·16 enrolled
Tadalafil Effects in Left Ventricle Diastolic Dysfunction in Resistant Hypertensive Patients
Completed·UUniversity of Campinas, Brazil·N/A·NCT01743911·20 enrolled
Effect of Ranolazine on Echocardiographic Indices of Diastolic Dysfunction
Terminated·UUniversity of California, San Diego·N/A·NCT00574756·14 enrolled
Angiotensin-Neprilysin Inhibition in Diastolic Dysfunction After AMI
Terminated·—·Phase 2·NCT04149990·51 enrolled
Prevention of Age-associated Cardiac and Vascular Dysfunction Through Nrf2 Signaling Using the Nutritional Supplement Sulforaphane
Withdrawn·TTexas Tech University Health Sciences Center·Preclinical·NCT05408559
Effects of Remifentanil on Cardiac Function in Patients With Diastolic Dysfunction
Unknown status·YYeditepe University·Phase 4·NCT04117009·30 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)