/
Other
Efficacy
140
Pipeline Programs↗
131
Active Trials↗
214
Companies Involved↗
Efficacy is a highly competitive landscape with 140 programs across 214 companies. The most active players are Revolution Medicines, Tango Therapeutics, Inc., Ono Pharmaceutical Co. Ltd. 35 programs are in Phase 3.
Intelligence
Pipeline Metrics
Competitive Density
Pipeline Velocity
Mech. Concentration
Completion Rate
Attrition Rate
Competition
Competitive Landscape
Bubble size = clinical trials
Approved
Phase 3
Phase 2
Phase 1
Preclinical
Key Players
Top Companies Companies ranked by the number of pipeline programs they run for this disease.
Pipeline
Programs by Phase
Preclinical40
Phase 116
Phase 249
Phase 335
Approved
No programs
Analysis
Modality Breakdown
89%
Small molecule
116 of 130 classified programs — the dominant modality here.
Small molecule leads; the ring shows all 130 classified programs, each share of the total. Modality classified for 100% of 140 pipeline programs.
Analysis
Trial Status
1,162
clinical trials
Completed754 · 65%
Unknown status136 · 12%
Terminated90 · 8%
Recruiting62 · 5%
Withdrawn45 · 4%
Not yet recruiting42 · 4%
Other33 · 3%
Clinical Trials
Trial Activity
1162 trials
A 20-Week Study Assessing the Efficacy of Apremilast in Patients with EB Simplex Generalized
Recruiting·—·Phase 2·NCT06509984·20 enrolled
Comparing the Efficacy of Oral Fluconazole Versus Oral Itraconazole in Treating Resistant Tinea Corporis
Recruiting·—·Phase 4·NCT07342153·126 enrolled
Novel Calcium Channel Modulators in RLS and Variants: Efficacy & Safety
Recruiting·—·Phase 1·NCT07453862·20 enrolled
Indicators and Evaluation of Efficacy of Yin-nourishing and Fire-reducing Chinese Medicine for Girls With Rapid Progression of Early Puberty
Recruiting·—·Phase 4·NCT06820931·80 enrolled
Study of the Safety, Tolerability, Electrophysiological Effects and Efficacy of DMT in Humans
Recruiting·—·Phase 1·NCT06671977·60 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)