VivoSeq
Other

Estrogen

1

Pipeline Programs↗

5

Active Trials↗

1

Companies Involved↗

Estrogen is an early-stage landscape with 1 program across 1 company. The most active players are Pfizer. 1 therapy is approved.

Intelligence

Pipeline Metrics

Competitive Density

22/100

Pipeline Velocity

6/100

Mech. Concentration

N/A

Completion Rate

86/100

Attrition Rate

11/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Pfizer logo

Pfizer

0 programs

Preclinical

Pipeline

Programs by Phase

Preclinical
No programs
Phase 1
No programs
Phase 2
No programs
Phase 3
No programs
Approved1

Ganirelix Acetate

Yale University

Analysis

Trial Status

47

clinical trials

Completed32 · 68%
Unknown status5 · 11%
Recruiting4 · 9%
Withdrawn3 · 6%
Terminated2 · 4%
Active, not recruiting1 · 2%

Clinical Trials

Trial Activity

47 trials

Cardiac Outcomes With Near-Complete Estrogen Deprivation
Recruiting·—·N/A·NCT05309655·90 enrolled
Plasma Oxytocin Response to Oral Estrogens in Healthy Controls and AVP-Deficiency
Recruiting·UUniversity Hospital, Basel, Switzerland·N/A·NCT07361263·28 enrolled
Role of Estrogen on Skeletal Outcomes in FHA
Recruiting·UUniversity of Virginia·Phase 2·NCT07010146·150 enrolled
Disentangling the Effects of Daily Stress, Sleep, and Sex Hormones on Accelerated Vascular Aging in Midlife Women
Recruiting·UUniversity of Delaware·Approved·NCT06745466·30 enrolled
Phase IIB Trial of Bazedoxifene Plus Conjugated Estrogens
Active, not recruiting·UUniversity of Kansas Medical Center·Phase 2·NCT04821141·120 enrolled
Estrogen and Serotonin on Changing Brain Chemistry
Completed·UUniversity of Colorado, Denver·N/A·NCT01208324·47 enrolled
Heart and Estrogen-Progestin Replacement Study (HERS)
Completed·UUniversity of California, San Francisco·Phase 3·NCT00319566·2,430 enrolled
The Effects of Estrogen on Artificial Endometrium
Completed·MMemorial Sisli Hospital, Istanbul·N/A·NCT03155048·317 enrolled
Impact of Estrogen on Fear Extinction R61
Completed·NNYU Langone Health·Phase 1·NCT02673606·136 enrolled
Estrogen Hormone Protocol
Completed·National Institute on Aging (NIA)·Phase 3·NCT00000177·120 enrolled
Estrogen Receptor Beta and Mood
Completed·National Institute of Mental Health (NIMH)·Phase 2·NCT03689543·74 enrolled
Research Investigation of Soy and Estrogen
Completed·UUniversity of Illinois at Chicago·Phase 2·NCT00997893·96 enrolled
Isolated and Associated Effects of Physical Exercise and Estrogen Therapy on Climactercs Women
Completed·UUniversity of Sao Paulo General Hospital·N/A·NCT01120665·62 enrolled
Study Comparing Formulations of Bazedoxifene/Conjugated Estrogens
Completed·Pfizer logoPfizer·Phase 1·NCT00550303·28 enrolled
Effects of Acute Estrogen Therapy on Bone Formation
Completed·MMayo Clinic·Phase 1·NCT02349113·20 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)