VivoSeq
Other

Executive Function

16

Pipeline Programs↗

4

Active Trials↗

11

Companies Involved↗

Executive Function is an emerging landscape with 16 programs across 11 companies. The most active players are Pascoe Pharmazeutische Praeparate GmbH, Takeda, Promius Pharma, LLC. 10 therapies are approved with 1 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

44/100

Pipeline Velocity

11/100

Mech. Concentration

22/100

Completion Rate

92/100

Attrition Rate

5/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

P

Pascoe Pharmazeutische Praeparate GmbH

1 program

Phase 1Takeda logo

Takeda

3 programs

ApprovedP

Promius Pharma, LLC

1 program

ApprovedM

Map77

1 program

ApprovedNovartis logo

Novartis

1 program

ApprovedTeva logo

Teva

1 program

Approved

Pipeline

Programs by Phase

Analysis

Trial Status

19

clinical trials

Completed11 · 58%
Unknown status3 · 16%
Recruiting2 · 11%
Withdrawn1 · 5%
Active, not recruiting1 · 5%
Not yet recruiting1 · 5%

Clinical Trials

Trial Activity

19 trials

Differences by Sex and Genotype in the Effects of Stress on Executive Functions
Recruiting·UUniversity of British Columbia·Phase 1·NCT04273880·146 enrolled
An Open-Label Treatment With Randomization Observation, Investigator-Initiated Study, on the Duration and Efficacy of Jornay PM (Methylphenidate Hydrochloride Extended-Release Capsules) on Adult ADHD Symptoms and Executive Function and Emotional Regulation Throughout the Day Into Early Evening
Recruiting·NNYU Langone Health·Phase 4·NCT06577779·30 enrolled
Low-dose vs. Normal-dose Psychostimulants on Executive Functions in Individuals With ADHD
Active, not recruiting·UUniversity of British Columbia·Phase 1/2·NCT02167048·52 enrolled
Influence of a Parent-mediated mHealth Motor Skill Intervention on Preschool Children's Motor Skills and Cognitive Function
Not yet recruiting·UUniversity of Tennessee·Preclinical·NCT07680075·35 enrolled
Evaluation of Behavior, Executive Function, Neurotransmitter Function and Genomic Expression Kuvan Nonresponders
Completed·TTulane University School of Medicine·N/A·NCT01274026·21 enrolled
IMProving Executive Function Study
Completed·UUniversity of Pennsylvania·Phase 4·NCT03187353·69 enrolled
Duration and Efficacy of Azstarys on Adult ADHD Symptoms and Executive Function in Early Evening
Completed·NNYU Langone Health·Phase 4·NCT06000501·29 enrolled
Effects of Atx and Oros-mph on Executive Functions
Completed·TTC Erciyes University·Phase 4·NCT02352051·43 enrolled
Efficacy of GXR as Adjunctive Therapy With Psycho-stimulant on Executive Function in Children With ADHD
Completed·JJPM van Stralen Medicine Professional·Phase 4·NCT01985581·50 enrolled
Evaluating the Impact of Quitting Using Executive Function Strategy Training (QUEST) on Smoking Cessation in Homeless Young Adult Smokers
Completed·OOhio State University Comprehensive Cancer Center·N/A·NCT06745154·27 enrolled
Safety and Efficacy of SPD489 on Executive Function Behaviors in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)
Completed·Takeda logoTakeda·Phase 4·NCT01101022·161 enrolled
Study of the Duration and Efficacy of MYDAYIS on Adult ADHD Symptoms and Executive Function Throughout the Day Into the Early Evening
Completed·NNYU Langone Health·Phase 3·NCT03945175·52 enrolled
Effects of Soccer-Specific Cognitive-Motor Training on Executive Functions, Decision-Making, and Skill Performance in Soccer Players: A Randomized Controlled Trial
Completed·—·Preclinical·NCT07284940·64 enrolled
Multidimensional Evaluation of the Early Emergence of Executive Function and Emotional Regulation in Young Children in Bangladesh Using Nutritional and Psychosocial Intervention: A Pilot Study
Completed·BBoston Children's Hospital·Preclinical·NCT05629624·297 enrolled
Acute Effects of Moderate-Intensity Freestyle Swimming Exercise on Inhibitory Control, Cognitive Flexibility, and Selective Attention: A Randomized Controlled Trial
Completed·—·Preclinical·NCT07670104·60 enrolled
Page 1 of 2

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)