VivoSeq
Rare Disease

Fabry Disease

30

Pipeline Programs

21

Active Trials

18

Companies Involved

Fabry Disease is an emerging landscape with 30 programs across 18 companies. The most active players are Greenovation Biotech GmbH, Roche, Sangamo Therapeutics. 3 therapies are approved with 11 more in late-stage development.

Pipeline Metrics

Competitive Density

56/100

Pipeline Velocity

19/100

Mech. Concentration

50/100

Completion Rate

86/100

Attrition Rate

9/100

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Programs by Phase

Modality Breakdown

79%

Small molecule

22 of 28 classified programs — the dominant modality here.

21%ALL OTHERSProtein / enzyme621%

Small molecule leads; the ring shows all 28 classified programs, each share of the total. Modality classified for 95% of 37 pipeline programs.

Trial Status

80

clinical trials

Completed43 · 54%
Recruiting15 · 19%
Unknown status6 · 8%
Active, not recruiting5 · 6%
Terminated4 · 5%
Withdrawn3 · 4%
Other4 · 5%

Trial Activity

80 trials

Fabry Disease Registry Protocol
Recruiting·GGenzyme, a Sanofi Company·N/A·NCT00196742·9,000 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)