VivoSeq
Other

Fentanyl

4

Pipeline Programs↗

2

Active Trials↗

10

Companies Involved↗

Fentanyl is an early-stage landscape with 4 programs across 10 companies. The most active players are Purdue Pharma LP, Johnson & Johnson, Mylan Pharmaceuticals Inc.

Intelligence

Pipeline Metrics

Competitive Density

27/100

Pipeline Velocity

6/100

Mech. Concentration

100/100

Completion Rate

79/100

Attrition Rate

18/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

P

Purdue Pharma LP

1 program

Phase 2Johnson & Johnson logo

Johnson & Johnson

0 programs

PreclinicalMylan Pharmaceuticals Inc logo

Mylan Pharmaceuticals Inc

0 programs

PreclinicalY

YM BioSciences

0 programs

PreclinicalZ

ZARS Pharma Inc.

0 programs

PreclinicalKyowa Kirin Co., Ltd. logo

Kyowa Kirin Co., Ltd.

0 programs

Preclinical

Pipeline

Programs by Phase

Preclinical
No programs
Phase 1
No programs
Phase 24

Naloxone Hydrochloride

Purdue Pharma LP

Fentanyl

Cephalon

Sterile Saline

Clear Scientific, Inc.

CS-1103

Clear Scientific, Inc.

Phase 3
No programs
Approved
No programs

Analysis

Trial Status

50

clinical trials

Completed34 · 68%
Terminated8 · 16%
Unknown status5 · 10%
Recruiting2 · 4%
Withdrawn1 · 2%

Clinical Trials

Trial Activity

50 trials

Nebulized Fentanyl in Healthy Volunteers
Recruiting·UUniversity Hospital, Rouen·Phase 1·NCT06281951·20 enrolled
A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of a Single Dose of Intravenous CS 1103 Following a Single Intravenous Dose of Fentanyl in Healthy Subjects With Naloxone Blockade
Recruiting·CClear Scientific, Inc.·Phase 2·NCT07459166·16 enrolled
Intranasal Fentanyl in Preterm Infants Undergoing Peripherally Inserted Central Catheter Placement
Completed·MMount Sinai Hospital, Canada·Phase 3·NCT06590870·8 enrolled
Intranasal Fentanyl for Management of Pain Associated With Cystoscopic Procedures
Completed·RRichard C Reznichek, MD·Phase 1·NCT01756651·20 enrolled
Intranasal Ketamine Versus Intranasal Fentanyl
Completed·IIsfahan University of Medical Sciences·Phase 3·NCT04414800·125 enrolled
Bioequivalence and Wear Study of Mylan Fentanyl Transdermal System 25 µg/h and Mylan Fentanyl Transdermal System With Askina Derm Overlay
Completed·Mylan Pharmaceuticals Inc logoMylan Pharmaceuticals Inc·Phase 1·NCT00647686·80 enrolled
A Study to Assess the Relative Bioavailability of 4 Formulations of Fentanyl Transdermal System Compared Against DUROGESIC Fentanyl Transdermal Patch After Single Application in Healthy Volunteers
Completed·Johnson & Johnson logoJohnson & Johnson·Phase 1·NCT01717157·32 enrolled
Continuous Infusion of Fentanyl in Preterm on MV
Completed·IIRCCS Azienda Ospedaliero-Universitaria di Bologna·Phase 3·NCT00571636·128 enrolled
Study of Single and Multiple Doses of Inhaled AeroLEF (Liposome-Encapsulated Fentanyl)in Healthy Subjects
Completed·YYM BioSciences·Phase 1·NCT00709254·12 enrolled
Fentanyl Ultra Low Doses Effects on the Nociceptive Threshold
Completed·UUniversity Hospital, Bordeaux·Phase 4·NCT00454259·48 enrolled
Long-term Safety Study of Sublingual Fentanyl Tablets in Cancer Patients
Completed·Kyowa Kirin Co., Ltd. logoKyowa Kirin Co., Ltd.·Phase 3·NCT00263575·139 enrolled
IN Sub-Dissociative Ketamine vs IN Fentanyl
Completed·WWake Forest University Health Sciences·Phase 2·NCT02521415·87 enrolled
Bioequivalence and Wear Study of Mylan Fentanyl Transdermal System 25 µg/h and Mylan Fentanyl Transdermal System
Completed·Mylan Pharmaceuticals Inc logoMylan Pharmaceuticals Inc·Phase 1·NCT00650117·12 enrolled
Safety of Epidural Fentanyl and Adrenalin During Childbirth
Completed·OOslo University Hospital·Phase 4·NCT00685672·40 enrolled
Long-term Extension Study of BEMA™ Fentanyl
Completed·BBioDelivery Sciences International·Phase 3·NCT00696137·5 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)