VivoSeq
Cardiovascular

Heart Failure With Reduced Ejection Fraction (hfref)

1

Pipeline Programs↗

2

Active Trials↗

2

Companies Involved↗

Heart Failure With Reduced Ejection Fraction (HFrEF) is an early-stage landscape with 1 program across 2 companies. The most active players are Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA), Eli Lilly. 1 therapy is approved.

Intelligence

Pipeline Metrics

Competitive Density

16/100

Pipeline Velocity

11/100

Mech. Concentration

100/100

Completion Rate

100/100

Attrition Rate

0/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

C

Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

1 program

ApprovedEli Lilly logo

Eli Lilly

1 program

Approved

Pipeline

Programs by Phase

Preclinical
No programs
Phase 1
No programs
Phase 2
No programs
Phase 3
No programs
Approved1

Vericiguat

Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Analysis

Trial Status

3

clinical trials

Not yet recruiting2 · 67%
Completed1 · 33%

Clinical Trials

Trial Activity

Comparing the Efficacy and Safety of Vericiguat With Standard Medical Treatment in Patients With Heart Failure and Reduced Ejection Fraction: Randomized, Placebo-controlled, Parallel-group, Double-blind Trial
Not yet recruiting·National Institute of Cardiovascular Diseases, Pakistan·Approved·NCT07697833·500 enrolled
Effectiveness of Video Monitoring and Care Transition for Heart Failure Patients (EVIT-HF): Randomized Clinical Trial
Completed·Federal University of Uberlandia·Preclinical·NCT06731166·140 enrolled
Implementation of an Encounter-based Patient Decision Aid for Heart Failure Medications in Heart Function Clinics: the SHARE-HF Pragmatic, Stepped-wedge Trial
Not yet recruiting·UUniversity of British Columbia·Preclinical·NCT07670845·1,350 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)