VivoSeq
Infectious Disease

Histoplasmosis

13

Pipeline Programs

3

Active Trials

8

Companies Involved

Histoplasmosis is an emerging landscape with 13 programs across 8 companies. The most active players are Regeneron, Roche, Pfizer's Upjohn has merged with Mylan to form Viatris Inc.. 1 therapy is approved with 6 more in late-stage development.

Pipeline Metrics

Competitive Density

41/100

Pipeline Velocity

11/100

Mech. Concentration

50/100

Completion Rate

89/100

Attrition Rate

7/100

Programs by Phase

Modality Breakdown

87%

Small molecule

13 of 15 classified programs — the dominant modality here.

13%ALL OTHERSMonoclonal antibody17%Protein / enzyme17%

Small molecule leads; the ring shows all 15 classified programs, each share of the total. Modality classified for 94% of 16 pipeline programs.

Trial Status

14

clinical trials

Completed8 · 57%
Unknown status2 · 14%
Recruiting2 · 14%
Terminated1 · 7%
Not yet recruiting1 · 7%

Trial Activity

14 trials

Macugen for Histoplasmosis
Terminated·BBarnes Retina Institute·N/A·NCT00272766·24 enrolled
Treatment for Presumed Ocular Histoplasmosis
Unknown status··Phase 1/2·NCT01790893·40 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)