VivoSeq
Other

Hydrocephalus

7

Pipeline Programs↗

5

Active Trials↗

5

Companies Involved↗

Hydrocephalus is an early-stage landscape with 7 programs across 5 companies. The most active players are Maastricht Radiation Oncology, McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc., Omnivium. 1 therapy is approved with 2 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

35/100

Pipeline Velocity

15/100

Mech. Concentration

25/100

Completion Rate

33/100

Attrition Rate

25/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

M

Maastricht Radiation Oncology

1 program

Phase 2M

McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

1 program

Phase 3O

Omnivium

1 program

ApprovedP

Prism Pharmaceuticals

1 program

PreclinicalR

Rhaeos, Inc.

0 programs

Preclinical

Pipeline

Programs by Phase

Analysis

Trial Status

8

clinical trials

Not yet recruiting3 · 38%
Recruiting2 · 25%
Terminated1 · 13%
Completed1 · 13%
Withdrawn1 · 13%

Clinical Trials

Trial Activity

8 trials

The Safety and Efficacy of Rapamycin on Communicating Hydrocephalus Secondary to Intraventricular Hemorrhage
Recruiting·—·Phase 2·NCT06563817·53 enrolled
Assessing CSF Flow Dynamics in Pediatric Hemorrhagic Hydrocephalus
Recruiting·—·Phase 1·NCT06994949·20 enrolled
Role of Endoscopic Third Ventriculostomy in Management of Hydrocephalus in Pediatric Age Group; Clinical and Surgical Outcome
Not yet recruiting·SSohag University·Preclinical·NCT07694518·30 enrolled
A Prospective Study Comparing CSF Shunt Flow Between "Virtual Off" and "Flow-Permissive" Shunt Valve Settings Using a Wireless, Noninvasive Shunt Flow Sensor
Not yet recruiting·RRhaeos, Inc.·Preclinical·NCT07679035·85 enrolled
VENTURE-PHH: Ventricular mTOR Inhibition to Prevent Hydrocephalus After Brain Hemorrhage
Not yet recruiting·MMassachusetts General Hospital·Preclinical·NCT07662174·15 enrolled
Cerebrospinal Fluid Proteome in Hydrocephalus
Completed·UUniversity Hospital, Toulouse·N/A·NCT02016352·100 enrolled
Isoflurane-induced Neuroinflammation in Children With Hydrocephalus
Terminated·NNationwide Children's Hospital·Phase 3·NCT02512809·25 enrolled
Contrast Enhanced Ultrasound Evaluation of Brain Perfusion in Neonatal Post-Hemorrhagic Hydrocephalus
Withdrawn·JJohns Hopkins University·Phase 4·NCT03061045

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)