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Other/Immune Function

Immune Function

3

Pipeline Programs↗

6

Active Trials↗

3

Companies Involved↗

Immune Function is an early-stage landscape with 3 programs across 3 companies.

Intelligence

Pipeline Metrics

Competitive Density

29/100

Pipeline Velocity

15/100

Mech. Concentration

N/A

Completion Rate

91/100

Attrition Rate

5/100

Pipeline

Programs by Phase

Preclinical2

Epidural Fentanyl

Zagazig University

Tdap

Pfizer

Phase 11

CAR T Cells

Chongqing Precision Biotech Co., Ltd

Phase 2

No programs

Phase 3

No programs

Approved

No programs

Analysis

Modality Breakdown

2programs

Small molecule150%

Cell therapy150%

Modality classified for 100% of 3 pipeline programs.

Analysis

Trial Status

19

clinical trials

Completed10 · 53%

Recruiting4 · 21%

Unknown status2 · 11%

Enrolling by invitation2 · 11%

Terminated1 · 5%

Clinical Trials

Trial Activity

19 trials

PCOS Immune Function Predicts Metformin Efficacy

Recruiting·SShanghai 10th People's Hospital·N/A·NCT06325956·100 enrolled

The Effect of Chimeric Antigen Receptor (CAR)-T Cell Therapy on the Reconstitution of HIV-specific Immune Function

Recruiting·GGuangzhou 8th People's Hospital·Phase 1·NCT03240328·40 enrolled

Study on the Mechanism of Yifei Moxibustion Improving Immune Function in COPD Based on Plasma Exosome miRNAs

Recruiting·HHenan University of Traditional Chinese Medicine·N/A·NCT07131020·120 enrolled

Randomized, Double-Blind, Controlled Study on the Effects of Continuous Yogurt Intake on Immunomodulatory Function and Subjective Health Status in Healthy U.S. Adults

Recruiting·MMeiji Co., Ltd.·Preclinical·NCT07799207·118 enrolled

Dynamic Effects of Different Anesthetic Agents on the Immune Function of Healthy Volunteers

Enrolling by invitation·HHenan Provincial People's Hospital·N/A·NCT07268872·80 enrolled

Safety, Efficacy of FFP From Healthy Donors to Ameliorate Frailty and Enhance Immune Function in Older Individuals

Enrolling by invitation·—·Phase 1/2·NCT03458429·30 enrolled

Effect of Red Ginseng Extract on Changes in Indicators of Immune Function in Vietnamese Healthy Volunteers

Completed·—·Phase 1·NCT05480774·101 enrolled

A Study of the Effectiveness of an HIV Vaccine (ALVAC vCP205) to Boost Immune Functions in HIV-Negative Volunteers Who Have Already Received an HIV Vaccine

Completed·National Institute of Allergy and Infectious Diseases (NIAID)·Phase 1·NCT00001136·60 enrolled

Immune Function and Muscle Adaptations to Resistance Exercise in Older Adults

Completed·VVA Office of Research and Development·N/A·NCT02261961·59 enrolled

Effects of Consumption of Orange Juice on Vascular Protection and Immune Function: Clinical Study on the Specific Contribution of Citrus Flavanones

Completed·UUniversity Hospital, Clermont-Ferrand·Phase 1·NCT00983086·24 enrolled

Assessment of the Effects of a DPP-4 Inhibitor (Sitagliptin) Januvia on Immune Function in Healthy Individuals

Completed·National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)·Phase 1·NCT00813228·76 enrolled

The Effct of Chitooligosaccharide on Immune Function in Healthy Adults

Completed·EEulji University Hospital·Phase 4·NCT00468962

Dipeptidyl Peptidase-4 Inhibition and Immune Function in HIV

Completed·WWashington University School of Medicine·Phase 2/3·NCT01093651·20 enrolled

Effects of Vitamin D3 Versus 25OHD3 on Mineral Metabolism and Immune Function

Completed·UUniversity of California, Los Angeles·Phase 1·NCT02091219·35 enrolled

Characterization of the Relationship Between the Human Mesolimbic Reward System and Immune Functioning

Completed·TTel-Aviv Sourasky Medical Center·N/A·NCT03951870·85 enrolled

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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)