VivoSeq
Other

Keratosis

13

Pipeline Programs↗

1

Active Trials↗

5

Companies Involved↗

Keratosis is an emerging landscape with 13 programs across 5 companies. The most active players are Aclaris Therapeutics, Inc., Bayer, LEO Pharma. 3 therapies are approved.

Intelligence

Pipeline Metrics

Competitive Density

40/100

Pipeline Velocity

0/100

Mech. Concentration

20/100

Completion Rate

93/100

Attrition Rate

4/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

A

Aclaris Therapeutics, Inc.

1 program

Phase 2Bayer logo

Bayer

1 program

Phase 2LEO Pharma logo

LEO Pharma

1 program

Phase 2Novartis logo

Novartis

1 program

ApprovedSun Pharmaceutical Industries, Inc. logo

Sun Pharmaceutical Industries, Inc.

1 program

Approved

Pipeline

Programs by Phase

Analysis

Trial Status

23

clinical trials

Completed13 · 57%
Unknown status8 · 35%
Recruiting1 · 4%
Terminated1 · 4%

Clinical Trials

Trial Activity

23 trials

A Trial to Evaluate the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Seborrheic Keratosis
Recruiting·DDermBiont, Inc.·Phase 2·NCT06108024·60 enrolled
A Randomized, Vehicle-Controlled Study of 2 Concentrations of A-101 for the Treatment of Seborrheic Keratosis
Completed·AAclaris Therapeutics, Inc.·Phase 2·NCT03148691·253 enrolled
Effect of Vitamin E on Skin Aerobic Bacteria in Palmar Arsenical Keratosis
Completed·—·Phase 2·NCT02468518·45 enrolled
Dose-Response Profile of A-101 in Subjects With Seborrheic Keratosis
Completed·AAclaris Therapeutics, Inc.·Phase 2·NCT02160626·172 enrolled
A Study of A-101 Solution 40% in Subjects With Seborrheic Keratosis.
Completed·AAclaris Therapeutics, Inc.·Phase 3·NCT02667236·450 enrolled
Earliest Stage Treatment of Aktinic Keratosis With Imiquimod 3.75% Cream
Completed·MMedical University of Graz·Phase 4·NCT04842422·48 enrolled
Effect of Neem Extract, Propylene Glycol and Salicylic Acid Combination in the Treatment of Arsenical Palmar Keratosis
Completed·—·Phase 2·NCT02352987·30 enrolled
A Randomized, Double-Blind, Vehicle-Controlled Study in Subjects With Seborrheic Keratosis
Completed·AAclaris Therapeutics, Inc.·Phase 3·NCT02667275·487 enrolled
Long-pulsed 1064 nm Nd-YAG Laser Versus TCA 20% in Treatment of Keratosis Pilaris
Completed·—·Phase 4·NCT04797663·20 enrolled
Treatment of Plantar Keratosis With Medicinal Plant in Diabetic Patients
Completed·UUniversidade do Vale do Sapucai·Phase 2·NCT03447925·90 enrolled
Study of A-101 for the Treatment of Seborrheic Keratosis
Completed·AAclaris Therapeutics, Inc.·Phase 2·NCT02260180·119 enrolled
Effects of Leaf Extract of Azadirachta Indica in Palmer Arsenical Keratosis
Completed·—·N/A·NCT01731756·50 enrolled
Study to Evaluate the Safety and Efficacy of PEP005(Ingenol Mebutate) Gel, 0.05%, in Patients With Seborrhoeic Keratosis
Completed·PPeplin·Phase 2·NCT01214564·24 enrolled
Study of Safety, Tolerability and Effectiveness of A-101 in Subjects With Seborrheic Keratosis
Completed·AAclaris Therapeutics, Inc.·Phase 1/2·NCT01986920·35 enrolled
Efficacy and Safety of Salkera Emollient Foam in the Treatment of Moderate to Severe Keratosis Pilaris, a Prospective Study
Terminated·WWright State University·Phase 4·NCT00944216·1 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)