VivoSeq
Other

Lower Urinary Tract Symptom

30

Pipeline Programs↗

3

Active Trials↗

17

Companies Involved↗

Lower Urinary Tract Symptom is an emerging landscape with 30 programs across 17 companies. The most active players are Spectrum Pharmaceuticals, Inc, Antipodean Pharmaceuticals, Inc., Mylan Pharmaceuticals Inc. 13 therapies are approved with 3 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

52/100

Pipeline Velocity

6/100

Mech. Concentration

9/100

Completion Rate

92/100

Attrition Rate

7/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Spectrum Pharmaceuticals, Inc logo

Spectrum Pharmaceuticals, Inc

1 program

Phase 2A

Antipodean Pharmaceuticals, Inc.

1 program

Phase 2Mylan Pharmaceuticals Inc logo

Mylan Pharmaceuticals Inc

1 program

Phase 3P

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

2 programs

ApprovedSanofi logo

Sanofi

1 program

ApprovedAbbVie logo

AbbVie

1 program

Approved

Pipeline

Programs by Phase

Analysis

Trial Status

45

clinical trials

Completed33 · 73%
Unknown status6 · 13%
Terminated3 · 7%
Recruiting2 · 4%
Not yet recruiting1 · 2%

Clinical Trials

Trial Activity

45 trials

Effect of Behavioral Sleep Intervention on Lower Urinary Tract Symptoms in Older Women
Recruiting·—·Phase 4·NCT05604222·120 enrolled
Testing MitoQ on Lower Urinary Tract Symptoms in Older Women With Metabolic Syndrome
Recruiting·—·Phase 2·NCT06351683·50 enrolled
Tadalafil 5 mg on Storage Lower Urinary Tract Symptoms After Anatomical Endoscopic Enucleation of the Prostate
Not yet recruiting·—·Phase 1·NCT07466030·40 enrolled
Efficacy and Safety of Tadalafil, Tamsulosin, and Their Combinations in Treating Lower Urinary Tract Symptoms in BPH Patients with Prostate Volumes ≤ 40 Ml: a Prospective Comparative Study
Completed·FFayoum University Hospital·Phase 4·NCT06809205·95 enrolled
Study the Effects of Different Doses of UK-369,003 in Men With Lower Urinary Tract Symptoms.
Completed·Pfizer logoPfizer·Phase 2·NCT00457457·609 enrolled
The Safety and Efficacy of Ozarelix to Treat Men With Lower Urinary Tract Symptoms Due to Enlargement of the Prostate
Completed·Spectrum Pharmaceuticals, Inc logoSpectrum Pharmaceuticals, Inc·Phase 2·NCT00427219·74 enrolled
Lucrin® Depot Efficacy and Safety Monitoring Study in Patients With Advanced Prostate Cancer and Lower Urinary Tract Symptoms (LUTS)
Completed·AAbbott·N/A·NCT01078545·729 enrolled
MCS in the Treatment of Lower Urinary Tract Symptoms
Completed·HHealth Ever Bio-Tech Co., Ltd.·Phase 2/3·NCT01002417·274 enrolled
Therapeutic Merit of Solifenacin in the Mitigation of Ureteral Stent-induced Pain and Lower Urinary Tract Symptoms
Completed·BBarrie Urology Associates·Phase 4·NCT01381120·84 enrolled
The Efficacy of Nano-water in Combination With Tamsulosin- Dutasteride for Lower Urinary Tract Symptoms
Completed·AALI KAMAL M. SAMI·N/A·NCT06677177·210 enrolled
Alfuzosin XL Lower Urinary Tract Symptoms Efficacy and Sexuality Study
Completed·Sanofi logoSanofi·Phase 4·NCT00575913·118 enrolled
Myrbetriq™ (Mirabegron) to Improve Disordered Sleep in Subjects With Lower Urinary Tract Symptoms (LUTS)
Completed·SSouthern Illinois University·N/A·NCT02410135·34 enrolled
Efficacy and Safety of MCS-2 in the Treatment of Lower Urinary Tract Symptoms
Completed·HHealth Ever Bio-Tech Co., Ltd.·Phase 3·NCT01002664·272 enrolled
Study of FLOMAX® Versus Placebo in Female Patients With Lower Urinary Tract Symptoms (LUTS) With a Significant Component of Voiding Symptoms
Completed·Boehringer Ingelheim logoBoehringer Ingelheim·Phase 2·NCT02244281·74 enrolled
Evaluation of Mirabegron Versus Tamsulosin or Their Combination in Treatment of Lower Urinary Tract Symptoms
Completed·—·N/A·NCT07307261·300 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)