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Other/Lung

Lung

10

Pipeline Programs↗

13

Active Trials↗

7

Companies Involved↗

Lung is an early-stage landscape with 10 programs across 7 companies. 1 program is in Phase 3.

Intelligence

Pipeline Metrics

Competitive Density

43/100

Pipeline Velocity

22/100

Mech. Concentration

20/100

Completion Rate

33/100

Attrition Rate

13/100

Pipeline

Programs by Phase

Preclinical1

129xe MRI Scans

Sean Fain

Phase 1

No programs

Phase 28

Etoposide

Avyxa

Cisplatin

McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Carboplatin

Avyxa

Adebrelimab

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Docetaxel

Avyxa

Phase 31

Cytalux

On Target Laboratories, LLC

Approved

No programs

Analysis

Modality Breakdown

67%

Small molecule

6 of 9 classified programs — the dominant modality here.

Small molecule leads; the ring shows all 9 classified programs, each share of the total. Modality classified for 90% of 10 pipeline programs.

Analysis

Trial Status

16

clinical trials

Recruiting7 · 44%

Active, not recruiting3 · 19%

Not yet recruiting3 · 19%

Completed1 · 6%

Withdrawn1 · 6%

Terminated1 · 6%

Clinical Trials

Trial Activity

16 trials

Characterization of the Pathogenesis of Lymphangioleiomyomatosis (LAM)

Recruiting·National Heart, Lung, and Blood Institute (NHLBI)·N/A·NCT00001465·2,000 enrolled

A Multicenter, Open-label, Single-arm Phase 2 Study to Evaluate the Efficacy and Safety of Luvometinib Combined With Anlotinib in Patients With KRAS-mutated Metastatic Non-small Cell Lung Cancer

Recruiting·SShanghai Fosun Pharmaceutical Industrial Development Co. Ltd.·Phase 2·NCT07562581·48 enrolled

The Shengjing Lung Cancer Cohort (SJ-LCC) Study

Recruiting·SShengjing Hospital·N/A·NCT07779005·1,500 enrolled

The Construction of a Digital Intelligence Early Warning System for the Whole Process of Acute Lung Injury in Liver Surgery Based on Cardiopulmonary Interaction Characteristics

Recruiting·BBeijing Tsinghua Chang Gung Hospital·N/A·NCT07070362·3,000 enrolled

Validation of MRI, CT and Pulmonary Function Tests for Early Detection of Chronic Lung Allograft Dysfunction

Recruiting·—·Preclinical·NCT06406777·100 enrolled

Quality of Life, Symptom Severity, and Care Needs in Lung Cancer Patients Receiving Immunotherapy

Recruiting·NNational Taiwan University Hospital·N/A·NCT06433206·180 enrolled

Non-intubated Thoracoscopic Surgery for Lung Leision in Patients With Impaired Pulmonary Function

Recruiting·TThe Second Hospital of Shandong University·Preclinical·NCT06848751·45 enrolled

Prospective Study on Detection and Prediction of Clinically Significant Pneumothorax After Image-guided Transthoracic Lung Biopsy

Active, not recruiting·CChinese University of Hong Kong·N/A·NCT06563167·330 enrolled

Prospective Realworld Cohort Study to Validate Effectiveness of an Artificial Intelligence Defined Lung Nodule Malignancy Score in Patients With Pulmonary Nodule Multicentric, Multinational, Prospective, Observational Study.

Active, not recruiting· AstraZeneca logo

AstraZeneca·N/A·NCT05817110·712 enrolled

A Phase 2 Study of Docetaxel, Ramucirumab, and Pembrolizumab for Patients With Metastatic or Recurrent Non-Small Cell Lung Cancer Who Progressed on Platinum-Doublet and PD-1/PD-L1 Blockade

Active, not recruiting·EEmory University·Phase 2·NCT04340882·30 enrolled

Iriscope for the Diagnosis of Peripheral Pulmonary Lesions: a Multicentre Randomised Controlled Trial

Not yet recruiting·EErasme University Hospital·Preclinical·NCT07798362·140 enrolled

Prospective, Multi Center, Open Label Non Inferiority Trial Evaluating the Clinical Adequacy of Intraoperative Tumor Fluorescence With Cytalux™ (Pafolacianine) Across Two Preoperative Administration Windows in Adults Undergoing Surgery for Suspected Lung Cancer or Confirmed Ovarian Cancer

Not yet recruiting·OOn Target Laboratories, LLC·Approved·NCT07469202·106 enrolled

Efficacy and Safety of Low-dose Thoracic Radiotherapy Followed by Adebrelimab Plus Chemotherapy and Sequential Adebrelimab Maintenance Therapy for Extensive-stage Small Cell Lung Cancer: A Prospective, Multicenter Phase II Study

Not yet recruiting·Jiangmen Central Hospital·Phase 2·NCT07583550·43 enrolled

Prediction of Weaning for Patients With Acute Brain Injury Undergoing Mechanical Ventilation

Completed·SSoutheast University, China·N/A·NCT06542107·605 enrolled

Robotic-assisted Bronchoscopy Under Moderate Sedation With Propofol: A Single-center Pilot Study.

Terminated·UUniversity of Zurich·Preclinical·NCT07006311·10 enrolled

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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)