VivoSeq
Other

Muscle Spasm

10

Pipeline Programs↗

0

Active Trials↗

9

Companies Involved↗

Muscle spasm is an early-stage landscape with 10 programs across 9 companies. The most active players are Novartis, Takeda, Averitas Pharma, Inc.. 6 therapies are approved with 2 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

36/100

Pipeline Velocity

0/100

Mech. Concentration

29/100

Completion Rate

100/100

Attrition Rate

0/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Novartis logo

Novartis

1 program

Phase 2Takeda logo

Takeda

1 program

Phase 3A

Averitas Pharma, Inc.

1 program

ApprovedAbbVie logo

AbbVie

1 program

ApprovedBayer logo

Bayer

1 program

ApprovedF

Fresenius Kabi Oncology Ltd.

1 program

Approved

Pipeline

Programs by Phase

Analysis

Trial Status

5

clinical trials

Completed5 · 100%

Clinical Trials

Trial Activity

Tolperisone in Acute Muscle Spasm of the Back
Completed·NNeurana Pharmaceuticals, Inc.·Phase 2·NCT03802565·415 enrolled
Safety and Efficacy of Baclofen for Treatment of Muscle Spasms in Patients With Cirrhosis: A Pilot Study
Completed·UUniversity of Virginia·Phase 2·NCT02298868·10 enrolled
Cyclobenzaprine HCl Extended Release 15 mg Versus Placebo in Treatment of Cervical and/or Lower Back Pain Due to Muscle Spasms of Local Origin
Completed·Takeda logoTakeda·Phase 3·NCT02814565·180 enrolled
Efficacy and Safety of Tolperisone in Subjects With Pain Due to Acute Back Muscle Spasm
Completed·NNeurana Pharmaceuticals, Inc.·Phase 3·NCT04671082·1,004 enrolled
An Effectiveness and Safety Study of Cyclobenzaprine HCl Alone or in Combination With Ibuprofen for Acute Back or Neck Muscle Pain With Muscle Spasm
Completed·MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.·Phase 4·NCT00246389·1,000 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)