VivoSeq
Other

Otitis Externa

11

Pipeline Programs↗

0

Active Trials↗

9

Companies Involved↗

Otitis Externa is an emerging landscape with 11 programs across 9 companies. The most active players are Otic Pharma, Cerimon Pharmaceuticals, Takeda. 3 therapies are approved with 5 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

37/100

Pipeline Velocity

0/100

Mech. Concentration

40/100

Completion Rate

71/100

Attrition Rate

27/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

O

Otic Pharma

2 programs

Phase 2C

Cerimon Pharmaceuticals

1 program

Phase 2Takeda logo

Takeda

2 programs

Phase 3P

Par Pharmaceutical, Inc.

2 programs

Phase 3Bayer logo

Bayer

1 program

Phase 3AbbVie logo

AbbVie

1 program

Phase 3

Pipeline

Programs by Phase

Analysis

Trial Status

15

clinical trials

Completed10 · 67%
Terminated4 · 27%
Unknown status1 · 7%

Clinical Trials

Trial Activity

15 trials

FST-201 in the Treatment of Acute Otitis Externa
Completed·Takeda logoTakeda·Phase 3·NCT00961675·70 enrolled
Phase 3 Study of OTO-201 in Acute Otitis Externa
Completed·OOtonomy, Inc.·Phase 3·NCT02801370·262 enrolled
A Phase III Study of an Otic Formulation in Acute Otitis Externa
Completed·AAlcon Research·Phase 3·NCT00750633·990 enrolled
OTO-201 for the Treatment of Otitis Externa
Completed·OOtonomy, Inc.·Phase 2·NCT02511561·75 enrolled
Efficacy and Safety of Once-Daily Ciprodexa Otic Foam Compared to Twice-daily Ciprodex Ear Drops in Acute Otitis Externa
Completed·OOtic Pharma·Phase 2·NCT01359098·100 enrolled
Comparative Efficacy and Safety of Ciprofloxacin 0.3% and Dexamethasone 0.1% in Acute Otitis Externa
Completed·EExela Pharma Sciences, LLC.·Phase 3·NCT02216071·499 enrolled
Efficacy and Safety of DF289 Plus DF277 Otic Solution in the Treatment of Acute Otitis Externa
Completed·SSalvat·Phase 3·NCT03196973·493 enrolled
Safety and Efficacy Evaluation of Topical AL-60371 Otic Suspension, 0.3% in the Treatment of Acute Otitis Externa
Completed·AAlcon Research·Phase 3·NCT01535599·768 enrolled
Safety and Efficacy Evaluation of Topical AL-60371 Otic Suspension, 0.3% in the Treatment of Acute Otitis Externa
Completed·AAlcon Research·Phase 3·NCT01535560·589 enrolled
Safety and Efficacy Study of Foam Otic Cipro Compared to a Standard Solution ( Ciloxan - Alcon Labs ) to Treat Acute Otitis Externa
Completed·OOtic Pharma·Phase 1/2·NCT00872209·100 enrolled
FST-201 In The Treatment of Acute Fungal Otitis Externa
Terminated·Takeda logoTakeda·Phase 3·NCT00945646·6 enrolled
FST-201 In The Treatment of Acute Otitis Externa
Terminated·Takeda logoTakeda·Phase 3·NCT00945802·5 enrolled
Topical Voltaren in Otitis Externa
Terminated·SSieff Medical Center·Phase 2·NCT00523120·20 enrolled
A Bioequivalence Study of Two Ciprofloxacin/Dexamethasone Formulations in Patients With Otitis Externa
Terminated·PPar Pharmaceutical, Inc.·Phase 3·NCT01910155·455 enrolled
A Phase III Study of Ciprofloxacin Plus Fluocinolone in Acute Otitis Externa (AOE)
Unknown status·LLee's Pharmaceutical Limited·Phase 3·NCT04636957·600 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)