VivoSeq
Metabolic & Endocrine

Overweight and Obesity

1

Pipeline Programs↗

4

Active Trials↗

3

Companies Involved↗

Overweight and Obesity is an early-stage landscape with 1 program across 3 companies. The most active players are AstraZeneca, Eli Lilly, Midwest Center for Metabolic and Cardiovascular Research.

Intelligence

Pipeline Metrics

Competitive Density

21/100

Pipeline Velocity

6/100

Mech. Concentration

N/A

Completion Rate

100/100

Attrition Rate

0/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

AstraZeneca logo

AstraZeneca

1 program

PreclinicalEli Lilly logo

Eli Lilly

1 program

PreclinicalM

Midwest Center for Metabolic and Cardiovascular Research

0 programs

Preclinical

Pipeline

Programs by Phase

Preclinical1

AZD9550

AstraZeneca

Phase 1
No programs
Phase 2
No programs
Phase 3
No programs
Approved
No programs

Analysis

Trial Status

11

clinical trials

Completed7 · 64%
Recruiting2 · 18%
Enrolling by invitation1 · 9%
Active, not recruiting1 · 9%

Clinical Trials

Trial Activity

11 trials

Taxi ROADmAP (Realizing Optimization Around Diet And Physical Activity)
Recruiting·MMemorial Sloan Kettering Cancer Center·Phase 2·NCT05770570·1,785 enrolled
Breathing & Blood Pressure
Recruiting·FFlorida State University·N/A·NCT05632406·80 enrolled
A Phase I/II, Randomised, Single-blind, Placebo-controlled, Multiple-ascending-dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD9550 Monotherapy and Co-administration of AZD9550 and AZD6234 in Participants Living With Obesity and Overweight With or Without Type 2 Diabetes Mellitus
Active, not recruiting·AstraZeneca logoAstraZeneca·Preclinical·NCT06151964·166 enrolled
Immersive Recreational Physical Exercise Program for Schoolchildren With Overweight or Obesity (PEESO)
Enrolling by invitation·University of Vigo·Preclinical·NCT07681856·36 enrolled
A Randomized Pilot Study of Produce Prescription Programs in Adults With Overweight or Obesity Experiencing Nutrition Insecurity
Completed·JJohns Hopkins University·Preclinical·NCT06751563·48 enrolled
A Health-literacy Module for Overweight Adolescents and Their Parents on Canine Physical Activity, Nutrition and Behavior: Enhancing Department of Health and Human Services' (DHHS) BodyWorks Program at a Federally Qualified Health Center
Completed·CChildren's Hospital Los Angeles·Preclinical·NCT04516252·202 enrolled
Fasting to Provide Energy Needed to Help Adults in Need of Cognitive Enhancement (FASTING ENHANCE)
Completed·UUniversity of Florida·Preclinical·NCT05732935·45 enrolled
Healthy Mothers-Healthy Children: An Intervention With Hispanic Mothers and Their Young Children
Completed·UUniversity of Miami·Preclinical·NCT03866902·578 enrolled
A Randomized, Parallel Trial to Assess the Effects of Replacing Non-fermented, Non-dairy Foods With Full-fat or Low-fat Fermented Dairy Foods on Insulin Sensitivity, RBC FA's and Other Markers of Cardiometabolic Health
Completed·MMidwest Center for Metabolic and Cardiovascular Research·Preclinical·NCT04999462·110 enrolled
The Effect of Tai Chi and Multimodal Exercise Programs on Balance in Overweight and Obese Women
Completed·PPamukkale University·Preclinical·NCT07536893·66 enrolled
Dietary Intervention With Probiotic Pasta and Evaluation of the Effects on Metabolic and Inflammatory Status in Overweight and Obese Subjects
Completed·FFederico II University·Preclinical·NCT04962633·40 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)