VivoSeq
Oncology

Pediatric Brain Tumor

0

Pipeline Programs↗

4

Active Trials↗

1

Companies Involved↗

Pediatric Brain Tumor is an early-stage landscape with 0 programs across 1 company. The most active players are Candel Therapeutics, Inc..

Intelligence

Pipeline Metrics

Competitive Density

16/100

Pipeline Velocity

11/100

Mech. Concentration

N/A

Completion Rate

50/100

Attrition Rate

31/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

C

Candel Therapeutics, Inc.

0 programs

Preclinical

Pipeline

Programs by Phase

No pipeline programs currently tracked for this disease.

Analysis

Trial Status

13

clinical trials

Completed4 · 31%
Terminated4 · 31%
Recruiting2 · 15%
Not yet recruiting2 · 15%
Unknown status1 · 8%

Clinical Trials

Trial Activity

13 trials

Intra-Tumoral Injections of Natural Killer Cells for Recurrent Malignant Pediatric Brain Tumors
Recruiting·SSabine Mueller, MD, PhD·Phase 1·NCT05887882·24 enrolled
Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)
Recruiting·—·Phase 1·NCT06193759·12 enrolled
Intratumoral DNX-2401 for High Grade Pediatric Brain Tumors
Not yet recruiting·—·Phase 2·NCT07424092·39 enrolled
A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors
Not yet recruiting·NNeonc Technologies, Inc.·Phase 1·NCT06357377·12 enrolled
Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors
Completed·SSidney Kimmel Comprehensive Cancer Center at Johns Hopkins·Phase 1·NCT02644291·16 enrolled
A Phase I Study of AdV-tk + Prodrug Therapy in Combination With Radiation Therapy for Pediatric Brain Tumors
Completed·CCandel Therapeutics, Inc.·Phase 1·NCT00634231·8 enrolled
Photodynamic Therapy (PDT) for Recurrent Pediatric Brain Tumors
Completed·HHarry T Whelan, MD·Phase 1·NCT01682746·5 enrolled
Comparison of PET and Proton MRS Imaging to Evaluate Pediatric Brain Tumor Activity
Completed·National Cancer Institute (NCI)·N/A·NCT00067821·79 enrolled
Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors
Terminated·WWashington University School of Medicine·Phase 2·NCT02372409·6 enrolled
FET-PET/MRI for Surgical Assessment of Pediatric Brain Tumors
Terminated·UUniversity of Alabama at Birmingham·Phase 1·NCT03451123·1 enrolled
Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors
Terminated·—·Phase 1·NCT01902771·1 enrolled
Therapeutic Targeting of Sex Differences in Pediatric Brain Tumor Glycolysis
Terminated·WWashington University School of Medicine·N/A·NCT03591861·2 enrolled
Tandem High Dose Chemotherapy and Autologous Stem Cell Rescue for High Risk Pediatric Brain Tumors
Unknown status·SSeoul National University Hospital·Phase 2·NCT01342237·33 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)