VivoSeq
Other

Physical Activity

36

Pipeline Programs↗

12

Active Trials↗

22

Companies Involved↗

Physical Activity is a moderately active landscape with 36 programs across 22 companies. The most active players are Validus Pharmaceuticals, Novo Nordisk, Eli Lilly. 6 therapies are approved with 8 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

56/100

Pipeline Velocity

19/100

Mech. Concentration

11/100

Completion Rate

89/100

Attrition Rate

7/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

V

Validus Pharmaceuticals

1 program

Phase 1Novo Nordisk logo

Novo Nordisk

2 programs

Phase 1Eli Lilly logo

Eli Lilly

2 programs

Phase 2EMD Serono logo

EMD Serono

1 program

Phase 2K

Kenvue Brands

1 program

Phase 2M

Mochida Pharmaceutical Company, Ltd.

1 program

Phase 2

Pipeline

Programs by Phase

Analysis

Modality Breakdown

88%

Small molecule

37 of 42 classified programs — the dominant modality here.

12%ALL OTHERSMonoclonal antibody37%Protein / enzyme25%

Small molecule leads; the ring shows all 42 classified programs, each share of the total. Modality classified for 100% of 43 pipeline programs.

Analysis

Trial Status

44

clinical trials

Completed25 · 57%
Active, not recruiting6 · 14%
Unknown status4 · 9%
Recruiting4 · 9%
Terminated3 · 7%
Not yet recruiting2 · 5%

Clinical Trials

Trial Activity

44 trials

Role of ET-1, Physical Activity, and Sedentary Behavior in Microvascular Dysfunction Following GDM
Recruiting·—·Phase 1·NCT06547619·40 enrolled
Impact of Physical Activity on Immunotherapy-induced Toxicities in Melanoma Management
Recruiting·UUniversity Hospital, Montpellier·N/A·NCT06627595·160 enrolled
Investigating Paclitaxel Toxicity in Breast Cancer: the Roles of Physical Activity and Body Composition.
Recruiting·UUniversitair Ziekenhuis Brussel·N/A·NCT06387901·40 enrolled
THE EFFECTS OF VIRTUAL REALITY AND VIDEO GAME-BASED EXERCISE PROGRAMS ON PHYSICAL FITNESS AND ATTENTION LEVELS IN HEALTHY ADOLESCENTS
Recruiting·Gaziantep Islam Science and Technology University·Preclinical·NCT07660822·48 enrolled
Anamorelin Hydrochloride, Physical Activity, and Nutritional Counseling in Decreasing Cancer-Related Fatigue in Patients With Incurable Metastatic or Recurrent Solid Tumors
Active, not recruiting·MM.D. Anderson Cancer Center·Phase 2·NCT03035409·129 enrolled
Physical Activity in Promoting Smoking Cessation in African Americans
Active, not recruiting·MM.D. Anderson Cancer Center·N/A·NCT01915810·45 enrolled
Supervised Physical Activity in Young Women With Early Breast Cancer During Neoadjuvant Chemotherpy
Active, not recruiting·TThe Greater Poland Cancer Centre·N/A·NCT06190600·40 enrolled
Physical Activity and Dexamethasone in Reducing Cancer-Related Fatigue in Patients With Advanced Cancer
Active, not recruiting·MM.D. Anderson Cancer Center·Phase 2/3·NCT02491632·90 enrolled
Vitamin D and Physical Activity on Bone Health
Active, not recruiting·UUniversity of Rochester·Phase 2·NCT01419730·191 enrolled
A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants With Severe or Moderate Hemophilia A Without Factor VIII Inhibitors on Emicizumab Prophylaxis
Active, not recruiting·Roche logoRoche·Phase 4·NCT05181618·136 enrolled
Investigating the Evolutionary Impact of Metabolic Flexibility on Physical Activity-Dependent BDNF and Cognition: Insights From the Val66Met Polymorphism
Not yet recruiting·UUniversity of Southern California·Phase 1·NCT07218497·50 enrolled
Incretin-based Therapies, Nutrition, and Physical Activity
Not yet recruiting·LLaval University·N/A·NCT07409831·120 enrolled
Study to Learn More About the Physical Activity Level of Patients Suffering From Hemophilia A Treated With Damoctocog Alfa Pegol (LIFE ACTIVE Study)
Completed·Bayer logoBayer·N/A·NCT04091386·10 enrolled
Effects of Zometa and Physical Activity on Bone Density in Women Receiving Chemotherapy for Breast Cancer
Completed·HHealthPartners Institute·Phase 3·NCT00202059·72 enrolled
An Observational Study to Evaluate Physical Activity, Bleeding Incidence and Health Related Quality of Life, in Participants With Haemophilia A Without Inhibitors Receiving Standard of Care Treatment
Completed·Roche logoRoche·N/A·NCT04165135·103 enrolled
Page 1 of 3

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)