VivoSeq
Infectious Disease

Poliomyelitis

16

Pipeline Programs↗

3

Active Trials↗

6

Companies Involved↗

Poliomyelitis is an emerging landscape with 16 programs across 6 companies. The most active players are CanSino Biologics Inc., GSK, Merck & Co.. 4 therapies are approved with 6 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

44/100

Pipeline Velocity

6/100

Mech. Concentration

N/A

Completion Rate

100/100

Attrition Rate

0/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

CanSino Biologics Inc. logo

CanSino Biologics Inc.

2 programs

Phase 1GSK logo

GSK

2 programs

Phase 1Merck & Co. logo

Merck & Co.

3 programs

Phase 3B

Beijing Minhai Biotechnology Co., Ltd

2 programs

Phase 3Sinovac Biotech Co., Ltd logo

Sinovac Biotech Co., Ltd

1 program

ApprovedSanofi logo

Sanofi

8 programs

Approved

Pipeline

Programs by Phase

Analysis

Modality Breakdown

82%

Vaccine

14 of 17 classified programs — the dominant modality here.

18%ALL OTHERSSmall molecule318%

Vaccine leads; the ring shows all 17 classified programs, each share of the total. Modality classified for 100% of 31 pipeline programs.

Analysis

Trial Status

25

clinical trials

Completed20 · 80%
Recruiting3 · 12%
Unknown status2 · 8%

Clinical Trials

Trial Activity

25 trials

Study of a Novel Type 1 Oral Poliomyelitis Vaccine in Bangladesh
Recruiting·PPATH·Phase 2·NCT05644184·2,232 enrolled
Study of Co-administered (Types 1 & 2) Novel Oral Poliomyelitis Vaccines Evaluation
Recruiting·PPATH·Phase 2·NCT06895486·675 enrolled
Study of Trivalent and Bivalent (Types 1 & 2) Novel Oral Poliomyelitis Vaccines
Recruiting·PPATH·Phase 1/2·NCT06137664·2,400 enrolled
Sequential Vaccination of Poliomyelitis Vaccine (Vero Cells), Inactivated, Sabin Strains From Different Manufacturers
Completed·Sinovac Biotech Co., Ltd logoSinovac Biotech Co., Ltd·Phase 4·NCT06346834·200 enrolled
A Study to Evaluate the Safety and Immunogenicity of Recombinant Trivalent Poliomyelitis Vaccine (Sf-RVN Cell) in Healthy Adults
Completed·CanSino Biologics Inc. logoCanSino Biologics Inc.·Phase 1·NCT06101173·72 enrolled
Immunogenicity and Safety of Concomitant and Non-Concomitant Administration of RotaTeq® (V260) and Inactivated Poliomyelitis Vaccine in Healthy Chinese Infants (V260-074)
Completed·Merck & Co. logoMerck & Co.·Phase 3·NCT04481191·400 enrolled
Consistency Study for Three Commercial Lots of Inactivated Poliomyelitis Vaccine Made From Sabin Strain
Completed·IInstitute of Medical Biology, Chinese Academy of Medical Sciences·Phase 4·NCT04224519·1,200 enrolled
Study of Tetanus and Diphtheria Toxoids Adsorbed Combined With Component Pertussis Vaccine and Inactivated Poliomyelitis
Completed·Sanofi logoSanofi·Phase 2·NCT02040636·277 enrolled
Study of Novel Types 1 and 3 Oral Poliomyelitis Vaccines
Completed·PPATH·Phase 1·NCT04529538·226 enrolled
The Clinical Trial Protocol for the Inactivated Poliomyelitis Vaccine Made From Sabin Strains
Completed·CChinese Academy of Medical Sciences·Phase 1·NCT01048190·130 enrolled
Study to Evaluate the Immune Response After Booster Vaccination With Tdap-IPV Vaccine (Against Tetanus, Diphtheria, Pertussis and Poliomyelitis) in Children Who Received Different Pertussis Primary Vaccine Regimens in Republic of South Africa
Completed·Sanofi logoSanofi·Phase 4·NCT04300192·273 enrolled
A Study to Evaluate Safety and Immunogenicity of Sequential Vaccination of Sabin Inactivated Poliomyelitis Vaccine (Vero Cell) and Live Attenuated Poliomyelitis Vaccine in Healthy 2-month-old Infants
Completed·BBeijing Minhai Biotechnology Co., Ltd·Phase 3·NCT06752174·300 enrolled
Sequential Inactivated Poliomyelitis Vaccine Followed by Oral Poliomyelitis Vaccine Versus Oral Poliomyelitis Vaccine
Completed·Sanofi logoSanofi·Phase 4·NCT01475539·456 enrolled
The Clinical Trial Protocol for the Inactivated Poliomyelitis Vaccine Made From Sabin Strains(Sabin IPV)
Completed·IInstitute of Medical Biology, Chinese Academy of Medical Sciences·Phase 3·NCT01510366·1,200 enrolled
The Clinical Trial Protocol for the Inactivated Poliomyelitis Vaccine Made From Sabin Strains (IPV)
Completed·CChinese Academy of Medical Sciences·Phase 2·NCT01056705·500 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)