VivoSeq
Other

Post Operative Nausea and Vomiting

30

Pipeline Programs↗

3

Active Trials↗

15

Companies Involved↗

Post Operative Nausea and Vomiting is an emerging landscape with 30 programs across 15 companies. The most active players are Novartis, GSK, Astellas. 19 therapies are approved with 5 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

52/100

Pipeline Velocity

19/100

Mech. Concentration

13/100

Completion Rate

86/100

Attrition Rate

9/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Novartis logo

Novartis

1 program

Phase 2GSK logo

GSK

1 program

Phase 3Astellas logo

Astellas

1 program

Phase 3Merck & Co. logo

Merck & Co.

1 program

Phase 3C

Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

2 programs

ApprovedA

Acacia Pharma Ltd

1 program

Approved

Pipeline

Programs by Phase

Analysis

Trial Status

11

clinical trials

Completed6 · 55%
Withdrawn1 · 9%
Recruiting1 · 9%
Unknown status1 · 9%
Not yet recruiting1 · 9%
Active, not recruiting1 · 9%

Clinical Trials

Trial Activity

11 trials

Preoperative Use of Pantoprazole for Prevention of Post Operative Nausea and Vomiting in Gynecologic Surgery
Recruiting·UUnited States Naval Medical Center, Portsmouth·Phase 2·NCT06488001·132 enrolled
Analysis of Risk Factors for Postoperative Nausea and Vomiting (PONV) in Adult Patients at the Post-Anaesthesia Care Unit (PACU) of RSUPN Dr. Cipto Mangunkusumo
Active, not recruiting·IIndonesia University·N/A·NCT07688811·280 enrolled
Efficacy and Safety Between Tegileridine and Sufentanil in Laparoscopic Surgery Patients at High Risk of Postoperative Nausea and Vomiting: A Prospective Observational Cohort Study
Not yet recruiting·SSecond Affiliated Hospital, School of Medicine, Zhejiang University·N/A·NCT07691086·800 enrolled
Casopitant And ZOFRAN To Prevent Post Operative Nausea And Vomiting In Women
Completed·GSK logoGSK·Phase 3·NCT00334152·515 enrolled
An Evaluation the Effect of Superhydration Versus Dextrose 10% for Prevention of Post Operative Nausea and Vomiting After Laparoscopic Cholecystectomy (prospective Randomised Controlled Study)
Completed·—·Phase 3·NCT06847594·204 enrolled
A Study To Evaluate An NK-1 Antiemetic For The Prevention Of Post Operative Nausea And Vomiting
Completed·GSK logoGSK·Phase 2·NCT00108095·701 enrolled
The Relationship Between Menstrual Cycle Phases and Postoperative Nausea and Vomiting: The Role of Sugammadex
Completed·SSakarya University·N/A·NCT07242209·60 enrolled
Intravenous Dexamethasone Palmitate for Prophylaxis of Postoperative Nausea and Vomiting After Minimally Invasive Endoscopic Surgery
Completed·BBeijing Tiantan Hospital·Preclinical·NCT06981754·588 enrolled
Effect of Adding Midazolam to Dual Prophylaxis of Dexamethasone and Ondansetron for Preventing Postoperative Nausea and Vomiting (PONV)
Completed·Hameed Latif Hospital, Lahore·Phase 2·NCT07668700·300 enrolled
Post Operative Nausea and Vomiting (PONV) Rescue Outcomes After Amisulpride Treatment
Withdrawn·AAcacia Pharma Ltd·N/A·NCT04954365
Study of Trimebutine Maleate (NEWBUTIN SR 300 mg Tab)for Treatment of Post Operative Nausea and Vomiting
Unknown status·—·Phase 3·NCT01984931·45 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)