VivoSeq
Other

Prediabetes

1

Pipeline Programs↗

16

Active Trials↗

5

Companies Involved↗

PreDiabetes is an early-stage landscape with 1 program across 5 companies. The most active players are Eli Lilly, Astellas, Novartis.

Intelligence

Pipeline Metrics

Competitive Density

34/100

Pipeline Velocity

34/100

Mech. Concentration

100/100

Completion Rate

96/100

Attrition Rate

2/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Eli Lilly logo

Eli Lilly

1 program

Phase 2Astellas logo

Astellas

1 program

Phase 2Novartis logo

Novartis

0 programs

PreclinicalSanofi logo

Sanofi

0 programs

PreclinicalA

Amway (China) R&D Center

0 programs

Preclinical

Pipeline

Programs by Phase

Preclinical
No programs
Phase 1
No programs
Phase 21

Mirabegron

Astellas

Phase 3
No programs
Approved
No programs

Analysis

Trial Status

43

clinical trials

Completed23 · 53%
Not yet recruiting8 · 19%
Recruiting8 · 19%
Unknown status3 · 7%
Withdrawn1 · 2%

Clinical Trials

Trial Activity

43 trials

Glucose and Glycogen Dynamics in Prediabetes
Recruiting·MMaastricht University Medical Center·N/A·NCT06317142·45 enrolled
Pharmacogenetics of the Response to GLP-1 in Mexican-Americans With Prediabetes
Recruiting·TThe University of Texas Health Science Center, Houston·Phase 4·NCT05119179·300 enrolled
The Role of Islet GLP-1 in the Pathogenesis of Prediabetes
Recruiting·MMayo Clinic·Phase 2·NCT06967558·60 enrolled
Effect of Metformin on Healthy Live Birth in Women With Prediabetes
Recruiting·SShandong University·N/A·NCT06064669·988 enrolled
Evaluation of Patient and Provider Facing EHR-embedded Risk Stratification Tools
Recruiting·UUniversity of California, Los Angeles·Preclinical·NCT06995378·1,200 enrolled
Mechanisms for Activation of Beige Adipose Tissue in Humans
Recruiting·—·Phase 2·NCT04666636·65 enrolled
Can Exogenous Ketone Supplementation Compensate for Glucose Hypometabolism and Improve Cognitive Processing Speed in Veterans With Prediabetes?
Recruiting·UUniversity of Alabama at Birmingham·Preclinical·NCT07546409·20 enrolled
Effects of Avocado on Triglyceride Metabolism in Individuals With Insulin Resistance
Recruiting·Clinical Nutrition Research Center, Illinois Institute of Technology·Preclinical·NCT07624500·82 enrolled
Reversal to Normoglycemia by Treating Prediabetes
Not yet recruiting·—·Phase 3·NCT07392151·158 enrolled
Henagliflozin's Impact on Prediabetes Remission
Not yet recruiting·SShandong Provincial Hospital·Phase 4·NCT06448130·984 enrolled
Pilot Trial of a Risk-informed Shared-decision Engagement Strategy
Not yet recruiting·JJohns Hopkins University·Preclinical·NCT07553325·120 enrolled
Subsidized Community Dining as Social Welfare Infrastructure for Healthy Aging: A Randomized Crossover Field Study of Postmeal Walking and Glycemic Profiles in Older Adults
Not yet recruiting·YYang ZHANG·Preclinical·NCT07695675·15 enrolled
Time to Healthy Lifestyle Habit Using Digital Health Tools in Adults at Risk of Diabetes: A Randomized Clinical Trial With Time-to-Habit Analysis
Not yet recruiting·IImam Abdulrahman Bin Faisal University·Preclinical·NCT07667361·222 enrolled
Trial of Continuous Glucose Monitoring (CGM) Technology in Persons Living With Prediabetes
Not yet recruiting·WWake Forest University Health Sciences·Preclinical·NCT07639593·100 enrolled
The Prevalence of Hyperglycemia in Surgical Patients With Pre-diabetes
Not yet recruiting·UUniversity of Calgary·N/A·NCT07662980·750 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)