VivoSeq
Other

Restless Leg Syndrome

0

Pipeline Programs↗

2

Active Trials↗

2

Companies Involved↗

Restless Leg Syndrome is an early-stage landscape with 0 programs across 2 companies. The most active players are UCB, Astellas.

Intelligence

Pipeline Metrics

Competitive Density

10/100

Pipeline Velocity

11/100

Mech. Concentration

N/A

Completion Rate

71/100

Attrition Rate

20/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

UCB logo

UCB

0 programs

PreclinicalAstellas logo

Astellas

0 programs

Preclinical

Pipeline

Programs by Phase

No pipeline programs currently tracked for this disease.

Analysis

Trial Status

10

clinical trials

Completed5 · 50%
Terminated2 · 20%
Active, not recruiting1 · 10%
Unknown status1 · 10%
Recruiting1 · 10%

Clinical Trials

Trial Activity

10 trials

The Effect of Spinal Cord Stimulators on Restless Leg Syndrome
Recruiting·UUniversity of Alabama at Birmingham·Preclinical·NCT07179406·50 enrolled
Benefits of a Cannabidiolic Acid Topical Cream for the Treatment of Restless Leg Syndrome
Active, not recruiting·SSynthonics Inc·Phase 1/2·NCT06570941·10 enrolled
Investigation of Efficacy of incobotulinumtoxinA (Xeomin) in Relieving Symptoms of Restless Leg Syndrome.
Completed·YYale University·Phase 2·NCT01931878·24 enrolled
Gabapentin Enacarbil (GSK1838262) Adult Restless Leg Syndrome (RLS) Post Marketing Commitment Study
Completed·XXenoPort, Inc.·Phase 4·NCT01668667·501 enrolled
Three Different Transdermal Doses of Rotigotine in Subjects With Idiopathic Restless Leg Syndrome
Completed·UCB logoUCB·Phase 3·NCT00136045·549 enrolled
Post-marketing Study of Gabapentin Enacarbil to Evaluate the Effect in Restless Leg Syndrome (RLS) Patients With Moderate Renal Impairment
Completed·Astellas logoAstellas·Phase 4·NCT01981941·19 enrolled
Effect of Transcutaneous Stellate Ganglion Electrical Stimulation on Restless Leg Syndrome in Hemodialysis Patients
Completed·CCairo University·Preclinical·NCT07657013·36 enrolled
Pramipexole for Restless Leg Syndrome in Peritoneal Dialysis Patients
Terminated·—·Phase 4·NCT03817554·21 enrolled
Blinded, Randomized Study of Gabapentin (Neurontin®) and Gabapentin Enacarbil (Horizant™) in Restless Leg Syndrome
Terminated·TTheresa Zesiewicz, MD·Phase 4·NCT02117076·5 enrolled
Treatment of Restless Leg Syndrome (RLS) Augmentation With Ecopipam, a D1 Specific Antagonist
Unknown status·WWilliam Ondo, MD·Phase 1/2·NCT03218969·10 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)