VivoSeq
Other

Severe Pain

0

Pipeline Programs↗

0

Active Trials↗

4

Companies Involved↗

Severe Pain is an early-stage landscape with 0 programs across 4 companies. The most active players are Tris Pharma, Inc., Olatec Therapeutics LLC, Bayer.

Intelligence

Pipeline Metrics

Competitive Density

0/100

Pipeline Velocity

0/100

Mech. Concentration

N/A

Completion Rate

69/100

Attrition Rate

31/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

T

Tris Pharma, Inc.

0 programs

PreclinicalO

Olatec Therapeutics LLC

0 programs

PreclinicalBayer logo

Bayer

0 programs

PreclinicalMenarini logo

Menarini

0 programs

Preclinical

Pipeline

Programs by Phase

No pipeline programs currently tracked for this disease.

Analysis

Trial Status

13

clinical trials

Completed9 · 69%
Terminated3 · 23%
Withdrawn1 · 8%

Clinical Trials

Trial Activity

13 trials

Protocolized vs Nonprotocolized Treatment of Adult ED Patients With Acute Severe Pain
Completed·MMontefiore Medical Center·Phase 3·NCT00627367·224 enrolled
A Trial Comparing Different Dosing Regimens of Morphine in Patients With Moderate to Severe Pain
Completed·MMontefiore Medical Center·N/A·NCT00293969·280 enrolled
Extension Study to Evaluate the Safety of Q8003 in Patients With Acute Moderate to Severe Pain
Completed·QQRxPharma Inc.·Phase 3·NCT00565760·16 enrolled
Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee
Completed·OOlatec Therapeutics LLC·Phase 2·NCT01768975·79 enrolled
Low Dose Ketamine Versus Morphine for Moderate to Severe Pain in the Emergency Department
Completed·—·Phase 4·NCT01835262·90 enrolled
Study to Find Out the Optimal Dose of Caffeine in the Combination Tablet of Naproxen Sodium and Caffeine in Patients Experiencing Moderate to Severe Pain After Having Wisdom Teeth Removed
Completed·Bayer logoBayer·Phase 2·NCT04132336·193 enrolled
Low Dose Ketamine for Management of Acute Severe Pain in the Emergency Department
Completed·RRhode Island Hospital·Phase 1·NCT01740492·75 enrolled
Analgesic Effect of Different Combinations of Dexketoprofen Trometamol With Tramadol Hydrochloride in a Model of Moderate to Severe Pain
Completed·Menarini logoMenarini·Phase 2·NCT01307020·745 enrolled
Safety of Hydromorphone in Adult Patients Presenting to the Emergency Department With Acute Severe Pain
Completed·MMontefiore Medical Center·Phase 2·NCT00305110·298 enrolled
Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain
Terminated·MMercy Health Ohio·Phase 4·NCT03959852·6 enrolled
CORAL - Cebranopadol Versus Morphine Prolonged-release in Patients With Chronic Moderate to Severe Pain Related to Cancer
Terminated·TTris Pharma, Inc.·Phase 3·NCT01964378·200 enrolled
A Dosing and Efficacy Study of Intra-nasal Sufentanil for Moderate to Severe Pain
Terminated·UUniversity of Utah·Phase 1/2·NCT01012999·16 enrolled
Fentanyl vs. Low-Dose Ketamine for the Relief of Moderate to Severe Pain in Aeromedical Patients
Withdrawn·UUniversity of Utah·N/A·NCT01169025

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)