VivoSeq
Other

Severe Pre-Eclampsia

9

Pipeline Programs↗

2

Active Trials↗

5

Companies Involved↗

Severe Pre-Eclampsia is an early-stage landscape with 9 programs across 5 companies. The most active players are Evergreen Therapeutics, Inc., Pfizer's Upjohn has merged with Mylan to form Viatris Inc., AstraZeneca. 6 therapies are approved.

Intelligence

Pipeline Metrics

Competitive Density

36/100

Pipeline Velocity

11/100

Mech. Concentration

25/100

Completion Rate

100/100

Attrition Rate

0/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

E

Evergreen Therapeutics, Inc.

1 program

Phase 1P

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

1 program

ApprovedAstraZeneca logo

AstraZeneca

1 program

ApprovedA

Advanz Pharma

1 program

ApprovedF

Fresenius Kabi Oncology Ltd.

1 program

Approved

Pipeline

Programs by Phase

Analysis

Trial Status

6

clinical trials

Completed3 · 50%
Not yet recruiting2 · 33%
Unknown status1 · 17%

Clinical Trials

Trial Activity

6 trials

Pharmacokinetic Study to Evaluate Safety and Tolerability of EG-101 in Healthy Female Volunteers as a Safety Lead-In for Dosing in Pregnant Women With Severe Pre-eclampsia
Not yet recruiting·EEvergreen Therapeutics, Inc.·Phase 1·NCT07327255·24 enrolled
Multicenter Randomized Trial of an sFlt-1/PlGF Ratio-Based Algorithm for Timing of Delivery in Early-Onset Severe Preeclampsia: The MAP 2 Study
Not yet recruiting·HHospital Clinic of Barcelona·Preclinical·NCT07665112·386 enrolled
Serum Magnesium Level Administration in Severe Pre-eclampsia Obese Pregnancy
Completed·Department of Medical Services Ministry of Public Health of Thailand·N/A·NCT03661775·60 enrolled
Efficacy and Safety of 1 g Vs 2 g Per Hour Intravenous Maintenance Dose of MgSO4 in Women With Severe Pre-eclampsia
Completed·—·Phase 4·NCT03164304·222 enrolled
Nitroglycerin Versus Labetalol in Acute Severe Pre-eclampsia
Completed·—·N/A·NCT05310929·200 enrolled
Anti-Hypertensive Treatment In Stable Pregnant Women With Severe Pre-Eclampsia (Metildopape)
Unknown status·PProfessor Fernando Figueira Integral Medicine Institute·Phase 4·NCT01361425·200 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)