VivoSeq
Other

Spironolactone

0

Pipeline Programs↗

4

Active Trials↗

5

Companies Involved↗

Spironolactone is an early-stage landscape with 0 programs across 5 companies. The most active players are Sarfez Pharmaceuticals, Inc., Pfizer, AstraZeneca.

Intelligence

Pipeline Metrics

Competitive Density

16/100

Pipeline Velocity

11/100

Mech. Concentration

N/A

Completion Rate

72/100

Attrition Rate

17/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

S

Sarfez Pharmaceuticals, Inc.

0 programs

PreclinicalPfizer logo

Pfizer

0 programs

PreclinicalAstraZeneca logo

AstraZeneca

0 programs

PreclinicalS

SPH Sine Pharmaceutical Laboratories Co., Ltd.

0 programs

PreclinicalOrion Corporation, Orion Pharma logo

Orion Corporation, Orion Pharma

0 programs

Preclinical

Pipeline

Programs by Phase

No pipeline programs currently tracked for this disease.

Analysis

Trial Status

35

clinical trials

Completed18 · 51%
Unknown status6 · 17%
Terminated4 · 11%
Withdrawn2 · 6%
Not yet recruiting2 · 6%
Enrolling by invitation1 · 3%
Other2 · 6%

Clinical Trials

Trial Activity

35 trials

Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne
Active, not recruiting·UUniversity of Pennsylvania·Phase 4·NCT04582383·350 enrolled
Topical 5% Spironolactone Gel Versus 0.1% Adapalene Gel for Acne Vulgaris: A Randomized Split-Face Study
Not yet recruiting·—·Phase 2·NCT07473895·40 enrolled
Comparative Study on the Mode of Action of Vicadrostat and Spironolactone on Protein Profiles and Renal Hemodynamic Effects (COMPARE-VS)
Not yet recruiting·UUniversity Medical Center Groningen·Phase 2·NCT07304817·100 enrolled
Spironolactone and XPB-1 Integrity in the TFIIH Complex
Enrolling by invitation·UUniversity of Sao Paulo General Hospital·N/A·NCT07415811·12 enrolled
A Study to Learn How the Body Processes Spironolactone and Hydrochlorothiazide Film Coated Tablets Manufactured at Two Sites: Viatris and Neolpharma
Completed·Pfizer logoPfizer·Phase 1·NCT06205407·42 enrolled
Randomized Double-blind Study on the Benefit of Spironolactone for Treating Acne of Adult Woman.
Completed·NNantes University Hospital·Phase 3·NCT03334682·158 enrolled
Colchicine and Spironolactone in Patients with MI / SYNERGY Stent Registry
Completed·PPopulation Health Research Institute·Phase 3·NCT03048825·7,264 enrolled
Effects of Cyproterone Compound-spironolactone, Metformin and Pioglitazone on Inflammatory Markers in PCOS
Completed·SShiraz University of Medical Sciences·Phase 1·NCT02689843·90 enrolled
Dapagliflozin With or Without Spironolactone for HFpEF
Completed·UUniversidade do Porto·Phase 2/3·NCT05676684·108 enrolled
Bioequivalence Study of Spironolactone Tablets in Healthy Subjects
Completed·SSPH Sine Pharmaceutical Laboratories Co., Ltd.·Phase 1·NCT06579053·64 enrolled
Spironolactone Improved Children With Gene Mutations Related to NCOR
Completed·QQilu Hospital of Shandong University·Phase 2/3·NCT06678685·2 enrolled
Spironolactone Therapy in Chronic Stable Right HF Trial
Completed·OOttawa Heart Institute Research Corporation·Phase 4·NCT03344159·15 enrolled
Bioavailability and Bioequivalence Study of Extended Release Torsemide and Spironolactone
Completed·SSarfez Pharmaceuticals, Inc.·Phase 3·NCT07046975·24 enrolled
Drug-drug Interaction (DDI) Study of Spironolactone (Perpetrator) and Digoxin (Substrate Drug)
Completed·CCMP Development, LLC·Phase 1·NCT03909529·28 enrolled
The Effect of Amiloride and Spironolactone in Healthy Persons
Completed·RRegional Hospital Holstebro·Phase 1·NCT00857909·30 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)