VivoSeq
Other

Sprain

32

Pipeline Programs↗

1

Active Trials↗

16

Companies Involved↗

Sprain is a moderately active landscape with 32 programs across 16 companies. The most active players are Cerimon Pharmaceuticals, Pfizer, APR Applied Pharma Research s.a.. 16 therapies are approved with 12 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

53/100

Pipeline Velocity

0/100

Mech. Concentration

43/100

Completion Rate

85/100

Attrition Rate

13/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

C

Cerimon Pharmaceuticals

1 program

Phase 3Pfizer logo

Pfizer

1 program

Phase 3A

APR Applied Pharma Research s.a.

1 program

Phase 3V

Vitae Pharmaceuticals Inc., an Allergan affiliate

1 program

Phase 3A

Amneal Pharmaceuticals, LLC

1 program

Phase 3GSK logo

GSK

2 programs

Approved

Pipeline

Programs by Phase

Analysis

Trial Status

38

clinical trials

Completed29 · 76%
Terminated4 · 11%
Unknown status3 · 8%
Withdrawn1 · 3%
Active, not recruiting1 · 3%

Clinical Trials

Trial Activity

38 trials

Topical Treatments for Ankle Sprains
Active, not recruiting·—·N/A·NCT06623929·100 enrolled
A Study of the Efficacy and Safety of Tramadol HCl/Acetaminophen, Hydrocodone Bitartrate/Acetaminophen and Placebo in Patients With Pain From an Ankle Sprain With a Partial Torn Ligament
Completed·Johnson & Johnson Pharmaceutical Research & Development, L.L.C. logoJohnson & Johnson Pharmaceutical Research & Development, L.L.C.·Phase 3·NCT00236535·603 enrolled
Open Label Comparative Study On Celecoxib Efficacy And Safety Vs Non-Selective NSAID In Acute Pain Due To Ankle Sprain
Completed·PPfizer's Upjohn has merged with Mylan to form Viatris Inc.·Phase 4·NCT00446797·278 enrolled
TAASS-Traumeel Ointment and Gel Compared With a Topical NSAID in Athletes With Acute Ankle Sprain
Completed·BBiologische Heilmittel Heel GmbH·Phase 3·NCT01066520·449 enrolled
Regular vs Intermittent Dose Ibuprofen for the Treatment of Ankle Sprains in Children
Completed·LLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·N/A·NCT01092676·100 enrolled
Injection of Corticoids for the Treatment of Acute Sprains of the Proximal Interphalangeal Joints of the Fingers.
Completed·—·Phase 2·NCT02916940·60 enrolled
Efficacy and Safety of Dexketoprofen/Vitamin B Vs Dexketoprofen for Post-traumatic Cervical Sprain Grade I-II
Completed·LLaboratorios Silanes S.A. de C.V.·Phase 3·NCT05001555·174 enrolled
Efficacy of Topical Indomethacin Patch Over Placebo in Ankle Sprain Pain Relief
Completed·GSK logoGSK·Phase 4·NCT01957215·270 enrolled
Voltaren Emulgel 2% Acute Ankle Sprain Non Inferiority Study
Completed·GSK logoGSK·Phase 3·NCT04052620·313 enrolled
Diclofenac Patch for Treatment of Acute Pain Due to Mild to Moderate Ankle Sprain
Completed·CCerimon Pharmaceuticals·Phase 3·NCT00869180·219 enrolled
Topical Ketoprofen Versus Placebo in Patients With Ankle Sprain
Completed·—·Phase 4·NCT02393846·100 enrolled
Efficacy and Safety of Diclofenac Diethylamine 2.32% Gel in Patients With Acute Ankle Sprain
Completed·Novartis logoNovartis·Phase 2·NCT00573768·271 enrolled
Efficacy and Safety of SST 0225, a Topical Ibuprofen Cream, in the Treatment of Pain Associated With Acute Ankle Sprain
Completed·SStrategic Science & Technologies, LLC·Phase 3·NCT01874626·305 enrolled
Evaluate the Efficacy and Safety of Diclofenac Diethylamine 2.32% Gel Applied Twice or Three Times Daily in Patients With Acute Ankle Sprain
Completed·Novartis logoNovartis·Phase 3·NCT00955513·242 enrolled
Approach to Ankle Sprains in the Emergency Department
Completed·—·Phase 4·NCT06563271·150 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)