VivoSeq
Other

Symptomatic Irreversible Pulpitis

4

Pipeline Programs↗

3

Active Trials↗

4

Companies Involved↗

Symptomatic Irreversible Pulpitis is an early-stage landscape with 4 programs across 4 companies. The most active players are Shanghai Argo Biopharmaceutical Co., Ltd., Bayer, Eli Lilly. 1 therapy is approved.

Intelligence

Pipeline Metrics

Competitive Density

28/100

Pipeline Velocity

19/100

Mech. Concentration

33/100

Completion Rate

100/100

Attrition Rate

0/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

S

Shanghai Argo Biopharmaceutical Co., Ltd.

1 program

ApprovedBayer logo

Bayer

1 program

PreclinicalEli Lilly logo

Eli Lilly

1 program

PreclinicalD

Dr Arsalan Ali Khan

0 programs

Preclinical

Pipeline

Programs by Phase

Analysis

Trial Status

7

clinical trials

Completed4 · 57%
Not yet recruiting2 · 29%
Recruiting1 · 14%

Clinical Trials

Trial Activity

7 trials

Comparison of the Effects of Submucosal and Intraligamentary Dexamethasone Administration on Anesthetic Success and Pain Control in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial
Recruiting·MMarmara University·Preclinical·NCT07672873·84 enrolled
Preoperative Intraligamentary Injection of Dexamethasone Can Improve the Anesthetic Success Rate of 2% Lidocaine During the Endodontic Management of Mandibular Molars With Symptomatic Irreversible Pulpitis
Not yet recruiting·WWatim Medical & Dental College·Approved·NCT07699315·60 enrolled
Effect of Using Ultrasonic Activated Irrigation, With and Without Intracanal Cryotherapy, on Post-Operative Pain After Single Visit Root Canal Treatment of Teeth With Symptomatic Irreversible Pulpitis: A Randomized Controlled Trial
Not yet recruiting·DDr Arsalan Ali Khan·Preclinical·NCT07663227·60 enrolled
The Relationship Between COMT, MAOA, and SLC6A4 Polymorphisms and the Success of Inferior Alveolar Nerve Block
Completed·MMarmara University·Preclinical·NCT07697300·95 enrolled
Effect of Preoperative Oral Ibuprofen on Anesthetic Efficacy of Inferior Alveolar Nerve Block With Supplemental Buccal and Lingual Infiltrations Using Articaine in Mandibular Molar Teeth With Irreversible Pulpitis: A Randomized Controlled Double-blind Study
Completed·CCairo University·Phase 1·NCT05927922·48 enrolled
Efficiency Of Intracanal Cryotherapy Versus Corticosteroids As Final Irrigation On Post Operative Pain Level In Patients With Symptomatic Irreversible Pulpitis Randomized Control Trial
Completed·OOctober 6 University·Approved·NCT07676396·40 enrolled
Effect of Preoperative Tramadol and Naproxen Sodium on Efficacy of Local Anesthesia and Post-operative Pain in Patients With Symptomatic Irreversible Pulpitis
Completed·DDow University of Health Sciences·Preclinical·NCT05982392·139 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)