VivoSeq
Other

Tendinopathy

27

Pipeline Programs↗

12

Active Trials↗

17

Companies Involved↗

Tendinopathy is an emerging landscape with 27 programs across 17 companies. The most active players are Pfizer's Upjohn has merged with Mylan to form Viatris Inc., ZARS Pharma Inc., Vitae Pharmaceuticals Inc., an Allergan affiliate. 6 therapies are approved with 5 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

53/100

Pipeline Velocity

19/100

Mech. Concentration

27/100

Completion Rate

68/100

Attrition Rate

20/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

P

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

1 program

Phase 1Z

ZARS Pharma Inc.

1 program

Phase 2V

Vitae Pharmaceuticals Inc., an Allergan affiliate

1 program

Phase 2EMD Serono logo

EMD Serono

1 program

Phase 2H

Hope Pharmaceuticals

1 program

Phase 2T

Taiwan Bio Therapeutics Inc.

1 program

Phase 3

Pipeline

Programs by Phase

Preclinical6

Naproxen Sodium

Bayer

Naproxen

Alnylam Pharmaceuticals

Glyceryl - Trinitrate

Procris Pharmaceuticals

Celgene

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Plathet Rich Plasma

Hospital Italiano de Buenos Aires

Phase 14

Collagenase Clostridium Histolyticum

Grupo Espanol de Tumores Neuroendocrinos

Doxycycline Hyclate

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

Prolotherapy

Mayo Clinic

Insulin-Like Growth Factor I

Children's Hospital of Philadelphia

Phase 26

Onabotulinumtoxina

Vitae Pharmaceuticals Inc., an Allergan affiliate

Lidocaine

MEDRx USA, Inc.

Platelet Rich Plasma

Zagazig University

Somatropin

EMD Serono

Sodium Thiosulfate

Hope Pharmaceuticals

Phase 35

Secukinumab

Novartis

Triamcinolone Acetonide

Bausch Health Americas, Inc.

Ketalar

Helse Møre og Romsdal HF

Platlet Rich Plasma

Tanta University

Celestone Cronodose (bethametasone)

Fundacion para la Investigacion Biomedica del Hospital Universitario Principe de Asturias

Approved6

Capsaicin

Averitas Pharma, Inc.

Etoricoxib

Novartis

Diclofenac

Novartis

Whole Blood

Versailles Hospital

CTM Boost

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Analysis

Modality Breakdown

95%

Small molecule

36 of 38 classified programs — the dominant modality here.

5%ALL OTHERSMonoclonal antibody13%Cell therapy13%

Small molecule leads; the ring shows all 38 classified programs, each share of the total. Modality classified for 100% of 50 pipeline programs.

Analysis

Trial Status

50

clinical trials

Completed21 · 42%
Unknown status7 · 14%
Withdrawn6 · 12%
Not yet recruiting4 · 8%
Active, not recruiting4 · 8%
Terminated4 · 8%
Other4 · 8%

Clinical Trials

Trial Activity

50 trials

Ketorolac in Upper Extremity Tendinopathy and Arthropathy
Recruiting·EEmory University·Phase 4·NCT05292339·160 enrolled
Nutrition Impact on PRGF Treatment for Tendinopathy
Recruiting·—·N/A·NCT06536582·52 enrolled
Efficacy of Therapeutic Percutaneous Electrolysis Simple vs Therapeutic Percutaneous Electrolysis Multifiliar Therapy in Supraspinatus Tendinopathy. Randomized Clinical Trial.
Recruiting·UUniversidad Pontificia de Salamanca·Preclinical·NCT07247825·40 enrolled
Effectiveness and Safety of OSTENIL® TENDON in the Treatment of Pain and Restricted Mobility in Tendon Disorders
Recruiting·TTRB Chemedica International SA·N/A·NCT06681051·84 enrolled
Connective Tissue Matrix for Rotator Cuff Tendinopathy
Active, not recruiting·—·Phase 4·NCT06160427·92 enrolled
Doxycycline for Elbow Tendinopathy
Active, not recruiting·HHospital for Special Surgery, New York·Phase 1·NCT04686799·25 enrolled
Effect of PRP vs Corticosteroid in Rotator Cuff Tendinopathy Subtypes in Arthroscopic Repair
Active, not recruiting·SSecond Affiliated Hospital, School of Medicine, Zhejiang University·Phase 4·NCT05603468·387 enrolled
Efficacy of Therapeutic Percutaneous Electrolysis Simple vs Multifiliar vs Laser Therapy in Supraspinatus Tendinopathy. Randomized Clinical Trial.
Active, not recruiting·UUniversidad Pontificia de Salamanca·Preclinical·NCT07695792·60 enrolled
The Analysis of Efficacy Factors for Autologous Platelet-Rich Plasma Therapy in the Treatment of Elbow Tendinopathy
Not yet recruiting·—·Phase 4·NCT06815042·30 enrolled
Effectiveness of Extracorporeal Shockwave Therapy Combined With Platelet-rich Plasma in the Treatment of Chronic Insertional Achilles Tendinopathy
Not yet recruiting·MMahidol University·Phase 4·NCT06384859·94 enrolled
Prospective Single-Arm Observational Study on the Efficacy and Safety of Ultrasound-Guided Peritendinous Injection of Low-Molecular-Weight Hyaluronic Acid (Hyalotend®; 500-730 kDa) for Chronic Non-Calcific Supraspinatus Tendinopathy.
Not yet recruiting·University Hospital of the Nuestra Señora de Candelaria·N/A·NCT07699406·30 enrolled
High-intensity Laser Therapy Versus Extracorporeal Shock Wave on Tendon Thickness and Occupation Ratio In Patients With Chronic Supraspinatus Tendinopathy
Not yet recruiting·CCairo University·Preclinical·NCT07667998·69 enrolled
Study Evaluating a Heated Lidocaine and Tetracaine Topical Patch in the Treatment of Patients With Patellar Tendinopathy
Completed·ZZARS Pharma Inc.·Phase 2·NCT01111773·13 enrolled
"NSAIDs in Acute Achilles Tendinopathy: Effect on Pain Control, Leg Stiffness and Functional Recovery in Athletes"
Completed·AArgentine Tennis Association·Phase 4·NCT00792376·56 enrolled
Treatment of Early Phase Achilles Tendinopathy - the Effect of NSAIDs
Completed·—·N/A·NCT03401177·70 enrolled
Page 1 of 4

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)