VivoSeq
Other

Tobacco Dependence

1

Pipeline Programs↗

1

Active Trials↗

0

Companies Involved↗

Tobacco Dependence is an early-stage landscape with 1 program across 0 companies. 1 therapy is approved.

Intelligence

Pipeline Metrics

Competitive Density

14/100

Pipeline Velocity

6/100

Mech. Concentration

N/A

Completion Rate

83/100

Attrition Rate

14/100

Pipeline

Programs by Phase

Preclinical
No programs
Phase 1
No programs
Phase 2
No programs
Phase 3
No programs
Approved1

Nicotine Replacement Product

Johns Hopkins University

Analysis

Trial Status

7

clinical trials

Completed5 · 71%
Terminated1 · 14%
Active, not recruiting1 · 14%

Clinical Trials

Trial Activity

7 trials

C-Raven: Pilot RCT of an Avatar-delivered Computerized Intervention for Tobacco Cessation With Community Health Worker Linkage to Lung Cancer Screening in Baltimore City (FY26)
Active, not recruiting·JJohns Hopkins University·Approved·NCT07220356·30 enrolled
Tobacco Dependence in Alcoholism Treatment (Nicotine Patch/Naltrexone)
Completed·TThe Scripps Research Institute·Phase 4·NCT00000437·60 enrolled
Optimizing Tobacco Dependence Treatment in the Emergency Department
Completed·YYale University·Phase 3·NCT02896400·1,056 enrolled
Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco Dependence
Completed·CCentre for Addiction and Mental Health·N/A·NCT03841292·41 enrolled
Translating Extinction Research to Improve Pharmacotherapy for Tobacco Dependence
Completed·HH. Lee Moffitt Cancer Center and Research Institute·Phase 1·NCT02202499·86 enrolled
Safety, Tolerability and Efficacy of the Nicotine Patch and Gum for the Treatment of Adolescent Tobacco Dependence
Completed·National Institute on Drug Abuse (NIDA)·Phase 2/3·NCT01208935·157 enrolled
Testing a Full Substitution Therapy Approach As Treatment of Tobacco Dependence
Terminated·CCentre for Addiction and Mental Health·N/A·NCT00390923·40 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)