VivoSeq
Other

X-Linked Hypophosphatemia

6

Pipeline Programs

3

Active Trials

5

Companies Involved

X-linked hypophosphatemia is an early-stage landscape with 6 programs across 5 companies. The most active players are Kyowa Kirin Co., Ltd., Alnylam Pharmaceuticals, Novartis. 1 therapy is approved with 1 more in late-stage development.

Pipeline Metrics

Competitive Density

32/100

Pipeline Velocity

0/100

Mech. Concentration

100/100

Completion Rate

100/100

Attrition Rate

0/100

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Programs by Phase

Modality Breakdown

80%

Small molecule

4 of 5 classified programs — the dominant modality here.

20%ALL OTHERSMonoclonal antibody120%

Small molecule leads; the ring shows all 5 classified programs, each share of the total. Modality classified for 100% of 6 pipeline programs.

Trial Status

16

clinical trials

Completed10 · 63%
Unknown status3 · 19%
Recruiting2 · 13%
Active, not recruiting1 · 6%

Trial Activity

16 trials

Calcitriol Monotherapy for X-Linked Hypophosphatemia
Active, not recruiting·MMassachusetts General Hospital·Phase 1·NCT03748966·20 enrolled
Calcitonin for Treating X-linked Hypophosphatemia
Completed·YYale University·N/A·NCT01652573·21 enrolled
A Study of KRN23 in X-linked Hypophosphatemia
Completed·Kyowa Kirin Co., Ltd. logoKyowa Kirin Co., Ltd.·Phase 1·NCT00830674·42 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)