Cocaine hydrochloride

Phase 3Small molecule

NNoden Pharma

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

ENT DisorderRecruiting

ENT DisorderPhase 3

Recruiting

Timeline

Expected Milestones

Q4 2027

Phase 3Recruiting

ENT Disorder

NCT04792034

Clinical

Trials by Indication[1]

Addiction2 trials

Investigation of Cocaine Addiction Using mGluR5 PET and fMRI

Completed·YYale University·Phase 1·NCT03471182·32 enrolled

Establishing and Eliminating Cue-drug Associations in Human Cocaine Addiction

Terminated·YYale University·Phase 1·NCT01978457·6 enrolled

Humans1 trial

Validation of a Remote Wireless Sensor Network (WSN) Approach to the Individualized Detection of Cocaine Use in Humans

Completed·YYale University·Phase 1·NCT02018263·5 enrolled

GLP-11 trial

GLP-1 Agonism for Blocking Cocaine Euphoria and Self-Administration

Completed·YYale University·Phase 1·NCT02302976·13 enrolled

Cardiovascular1 trial

Study to Improve Scientific Understanding of the Cardiovascular Actions of Cocaine

Withdrawn·UUniversity of Texas Southwestern Medical Center·Phase 1·NCT00338546

Interaction1 trial

Phase1, STP7 Cocaine Drug-Drug Interaction Study

Completed·SStalicla SA·Phase 1·NCT06273540·21 enrolled

3 more indications

Relapse1 trial

Effect of Zonisamide on Cocaine Reinforcement, Craving, and Relapse

Completed·JJohns Hopkins University·Phase 1/2·NCT01137890·19 enrolled

ENT Disorder1 trial

A Multicenter, Open-label, Two-Arm, Pharmacokinetics, Safety, and Tolerability Study of a Single Topical Dose of GOPRELTO® Nasal Solution and a Single Dose of NUMBRINO™ Nasal Solution for the Induction of Local Anesthesia of the Mucous Membranes When Performing Diagnostic Procedures and Surgeries in Pediatric Subjects From ≥12 Years to <18 Years of Age

Recruiting·NNoden Pharma·Phase 3·NCT04792034·40 enrolled

Unspecified1 trial

Impulsivity and Stimulant Administration

Completed·YYale University·Phase 1·NCT01978431·29 enrolled

Sources

References

[1]
ClinicalTrials.gov — 9 trial records for Cocaine hydrochloride. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Cocaine hydrochloride compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Cocaine hydrochloride. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Noden Pharma company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: NNoden Pharma