Linaprazan glurate

Phase 3Small molecule

CCinclus Pharma Holding AB

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

GERD (gastroesophageal Reflux Disease)Active, not recruiting

GERD (gastroesophageal Reflux Disease)Phase 3

Active, not recruiting

Timeline

Expected Milestones

Q4 2028

Phase 3Not yet recruiting

Gastroesophageal Reflux Disease

NCT07313774

Clinical

Trials by Indication[1]

Interaction1 trial

Drug Interaction Study on Linaprazan Glurate Capsules

Completed·JJiangsu Sinorda Biomedicine Co., Ltd·Phase 1·NCT07294846·56 enrolled

Midazolam1 trial

Effect of Clarithromycin on PK of Linaprazan, Linaprazan on PK of Clarithromycin and Linaprazan on PK of Midazolam

Completed·CCinclus Pharma Holding AB·Phase 1·NCT05633147·35 enrolled

Tics1 trial

A Study to Investigate the Pharmacokinetics and ECG Effects of Linaprazan Glurate

Unknown status·CCinclus Pharma AG·Phase 1·NCT05469854·113 enrolled

Gastroesophageal Reflux Disease1 trial

A Study Comparing the Effect and Safety of Linaprazan Glurate to Lansoprazole in Maintenance of Healing in Participants With Healed Erosive Esophagitis (EE) Due to Gastroesophageal Reflux Disease (GERD)

Not yet recruiting·CCinclus Pharma Holding AB·Phase 3·NCT07313774·1,050 enrolled

GERD (Gastroesophageal Reflux Disease)1 trial

A Randomized, Phase 3, Double-blind, Double-dummy, Active Comparator-controlled Multicenter Study to Evaluate the Efficacy and Safety of 2 Doses of Linaprazan Glurate Compared to Lansoprazole in 4 or 8 Weeks Healing in Participants With Erosive Esophagitis (EE) Due to Gastroesophageal Reflux Disease (GERD) of Los Angeles (LA) Grades A to D

Active, not recruiting·CCinclus Pharma Holding AB·Phase 3·NCT07037875·500 enrolled

1 more indication

Unspecified2 trials

Relative Bioavailability of Linaprazan for the Test Formulation vs. Reference Formulation

Completed·CCinclus Pharma Holding AB·Phase 1·NCT05627518·67 enrolled

Investigate Linaprazan Glurate/Linaprazan in Healthy Subjects

Completed·CCinclus Pharma Holding AB·Phase 1·NCT05742984·75 enrolled

Sources

References

[1]
ClinicalTrials.gov — 7 trial records for Linaprazan glurate. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Linaprazan glurate compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Linaprazan glurate. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Cinclus Pharma Holding AB company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: CCinclus Pharma Holding AB