Sodium Nitrate

Phase 2Small molecule

NNational Heart, Lung, and Blood Institute (NHLBI)

Sodium Nitrate is one of 118 small molecule programs targeting Muscular Dystrophy. It is currently in Phase 2.

Indications

Total Trials

Active Trials

117

Competitors

Pipeline

Status by Indication[3][1]

Indication

Muscular DystrophyActive, not recruiting

Acute Kidney InjuryActive, not recruiting

Hypertrophic CardiomyopathyActive, not recruiting

AsthmaActive, not recruiting

Muscular DystrophyPhase 1

Active, not recruiting

Acute Kidney InjuryPhase 2

Active, not recruiting

Hypertrophic CardiomyopathyPhase 1

Active, not recruiting

AsthmaPhase 2

Active, not recruiting

Competition

Competitive Landscape

1050 competitors in Asthma

#DrugCompanyPhaseTrials

Nucala

GGlaxo Dba Glaxosmithkline

Preclinical

35 2

Cinqair

Teva

Preclinical

13 3

Sodium Nitrate

NNational Heart, Lung, and Blood Institute (NHLBI)

Phase 2

1 4

Qvar

Chiesi Farmaceutici S.p.A.

Preclinical

8 5

Atrovent

Boehringer Ingelheim

Preclinical

5 6

Symbicort

AstraZeneca

Preclinical

6 7

Atrovent

Boehringer Ingelheim

Preclinical

2 8

Decadron

QQuince Therapeutics S.p.A.

Preclinical

1 9

Tylenol

KKenvue Brands

Preclinical

1 10

DUPIXENT

Regeneron

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Muscular Dystrophy1 trial

Sodium Nitrate for Muscular Dystrophy

Completed·—·Phase 1·NCT02434627·5 enrolled

Acute Kidney Injury1 trial

Inorganic Nitrate (NaNO3) Prevention of Contrast-Associated Acute Kidney Injury

Recruiting·UUniversity of Michigan·Phase 2·NCT07016074·100 enrolled

Asthma1 trial

The Effects of NOx and Conjugated Linoleic Acid on Asthmatics

Completed·GGladwin, Mark, MD·Phase 2·NCT02433977·6 enrolled

Cardiac1 trial

The Effects of Inorganic Nitrate on Cardiac Muscle in Angina

Completed·UUniversity of Aberdeen·Phase 2·NCT02078921·70 enrolled

Hypertrophic Cardiomyopathy1 trial

Nitrite in Hypertrophic Cardiomyopathy (HCM) Study

Unknown status·UUniversity of East Anglia·Phase 1·NCT03251287·18 enrolled

1 more indication

Preconditioning1 trial

The Role of Nitrite in Preconditioning Mediated Tolerance to Ischemic Stress

Completed·NNational Heart, Lung, and Blood Institute (NHLBI)·Phase 1·NCT00250185·135 enrolled

Sources

References

[1]
ClinicalTrials.gov — 6 trial records for Sodium Nitrate. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Sodium Nitrate compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Sodium Nitrate. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — National Heart, Lung, and Blood Institute (NHLBI) company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 2[1]
Company: NNational Heart, Lung, and Blood Institute (NHLBI)

Sodium Nitrate

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Muscular Dystrophy1 trial

Acute Kidney Injury1 trial

Asthma1 trial

Cardiac1 trial

Hypertrophic Cardiomyopathy1 trial

Preconditioning1 trial

References

Drug Info

Quick Facts

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