VivoSeq
Cardiovascular

Acute Ischemic Stroke

6

Pipeline Programs↗

13

Active Trials↗

8

Companies Involved↗

Acute Ischemic Stroke is an early-stage landscape with 6 programs across 8 companies. The most active players are Fujian Shengdi Pharmaceutical Co., Ltd., Suzhou Landing Pharmaceuticals, Neurodawn Pharmaceutical Co., Ltd.. 2 therapies are approved with 1 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

39/100

Pipeline Velocity

36/100

Mech. Concentration

N/A

Completion Rate

100/100

Attrition Rate

0/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

F

Fujian Shengdi Pharmaceutical Co., Ltd.

2 programs

Phase 2S

Suzhou Landing Pharmaceuticals

1 program

Phase 2N

Neurodawn Pharmaceutical Co., Ltd.

1 program

Phase 3Eli Lilly logo

Eli Lilly

1 program

ApprovedP

Perfuze

0 programs

PreclinicalA

Amrou Sarraj

0 programs

Preclinical

Pipeline

Programs by Phase

Analysis

Modality Breakdown

67%

Small molecule

4 of 6 classified programs — the dominant modality here.

33%ALL OTHERSProtein / enzyme117%Peptide117%

Small molecule leads; the ring shows all 6 classified programs, each share of the total. Modality classified for 46% of 13 pipeline programs.

Analysis

Trial Status

20

clinical trials

Recruiting8 · 40%
Completed7 · 35%
Not yet recruiting4 · 20%
Active, not recruiting1 · 5%

Clinical Trials

Trial Activity

20 trials

RIsEStroke (Recovery Insights Into Early Mobility Post Stroke)
Recruiting·WWake Forest University Health Sciences·Preclinical·NCT07638462·50 enrolled
Medical Management With Endovascular Thrombectomy Versus Medical Management Alone in Patients Presenting Beyond 24 Hours of Last Known Well - SELECT LATE Trial
Recruiting·—·Preclinical·NCT07115940·408 enrolled
The Pivotal Study of RapidPulseTM Aspiration System as Frontline Approach for Patient With Acute Ischemic Stroke Due to Large Vessel Occlusions
Recruiting·RRapidPulse, Inc·Preclinical·NCT06029491·170 enrolled
Repeated Intravenous Thrombolysis for Ischemic Stroke With Medium to Large Vessel Occlusion Presenting Within 4.5 Hours of Onset With Prourokinase (RITIS-PUK): a Prospective, Randomized, Open Label, Blinded Assessment of Outcome, and Multi-center Study
Recruiting·GGeneral Hospital of Shenyang Military Region·Phase 2·NCT07550296·122 enrolled
Effectiveness of Early Intervention With Virtual Reality-based Interactive Rehabilitation on Upper Extremity Muscle Strength, Cognitive Status, Hospital Anxiety and Exercise Self-efficacy in Patients With Acute Ischemic Stroke: A Randomized Controlled Trial
Recruiting·Tri-Service General Hospital (TSGH)·Preclinical·NCT07674329·100 enrolled
Efficacy and Safety of Sivelestat Sodium as an Adjunct to Endovascular Thrombectomy in Acute Anterior Circulation Large-Vessel Occlusion: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study
Recruiting·XXuanwu Hospital, Beijing·Preclinical·NCT07552610·868 enrolled
A Multicentric, Randomized, Double-blind, Parallel, Placebo-controlled Phase III Study to Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke.
Recruiting·PPharmazz, Inc.·Phase 3·NCT05691244·514 enrolled
Efficacy and Safety of Low-Dose Tenecteplase for Acute Ischemic Stroke Treatment in Aging Patients: A Prospective, Multicenter, Randomized Controlled Study
Recruiting·SSouthwest Hospital, China·Approved·NCT07294209·798 enrolled
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Safety and Efficacy of HRS-7450 Injection in Patients With Acute Ischemic Stroke.
Active, not recruiting·FFujian Shengdi Pharmaceutical Co., Ltd.·Phase 2·NCT07233070·210 enrolled
Efficacy and Safety of Sublingual Edaravone Dexborneol for Inter-hospital Transfer Acute Ischemic Stroke: A Multicenter, Randomized, Double-blind, Placebo-controlled Clinical Trial
Not yet recruiting·XXinqiao Hospital of Chongqing·Approved·NCT07682922·1,040 enrolled
Efficacy and Safety of Endovascular Therapy for Acute Basilar Artery Occlusion With Large Ischemic Core: A Prospective, Multicenter, Randomized Controlled Trial
Not yet recruiting·TThe First Affiliated Hospital of University of Science and Technology of China·Preclinical·NCT07672795·256 enrolled
Super Large Bore Catheter Aspiration Versus Stent Retriever Thrombectomy as First Line Technique for Anterior Circulation Large Vessel Occlusion in Acute Ischemic Stroke
Not yet recruiting·SShanghai Jiao Tong University Affiliated Sixth People's Hospital·Preclinical·NCT07555977·708 enrolled
Direct Angio Suite Acute Stroke Intervention With CT/DSA Hybrid Emergency Stroke Unit to Reduce Time to Endovascular Reperfusion for Acute Ischemic Stroke
Not yet recruiting·BBeijing Tiantan Hospital·Phase 3·NCT07670065·232 enrolled
Millipede AspiRation for Revascularization in Stroke (MARRS) Study
Completed·PPerfuze·Preclinical·NCT05714501·235 enrolled
Buyang Huanwu Decoction Combined With Wuling Powder as Adjunctive Therapy for Acute Ischemic Stroke: A Randomized, Assessor-Blinded, Controlled Clinical Study
Completed·LLiaoning University of Traditional Chinese Medicine·Preclinical·NCT07687043·102 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)