VivoSeq
Neurology

Cervical Dystonia

27

Pipeline Programs↗

6

Active Trials↗

14

Companies Involved↗

Cervical Dystonia is an emerging landscape with 27 programs across 14 companies. The most active players are AEON Biopharma, Inc., Neurocrine Biosciences, Teva. 7 therapies are approved with 3 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

51/100

Pipeline Velocity

11/100

Mech. Concentration

33/100

Completion Rate

92/100

Attrition Rate

4/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

A

AEON Biopharma, Inc.

1 program

Phase 2Neurocrine Biosciences logo

Neurocrine Biosciences

1 program

Phase 2Teva logo

Teva

1 program

Phase 2C

Catalyst Biosciences

1 program

Phase 2Alnylam Pharmaceuticals logo

Alnylam Pharmaceuticals

1 program

Phase 2R

Revance Therapeutics, Inc.

3 programs

Phase 3

Pipeline

Programs by Phase

Analysis

Trial Status

49

clinical trials

Completed34 · 69%
Unknown status6 · 12%
Recruiting4 · 8%
Not yet recruiting2 · 4%
Terminated2 · 4%
Suspended1 · 2%

Clinical Trials

Trial Activity

49 trials

Safety and Effectiveness of Valbenazine as Adjunct Therapy to Botulinum Toxin Injections in Cervical Dystonia
Recruiting·VVirginia Commonwealth University·Phase 2·NCT06771323·20 enrolled
Zinc as an Adjunctive Therapy for Cervical Dystonia
Recruiting·UUniversity of Florida·Phase 2·NCT07140874·20 enrolled
Theta Burst Transcranial Focused Ultrasound as a Novel Treatment for Cervical Dystonia
Recruiting·—·Preclinical·NCT07690514·48 enrolled
A Phase II, Multicentre, Randomised, Double-blind, Parallel-Group, Placebo Controlled Study to Evaluate the Efficacy and Safety of IPN10200 as a Treatment for Cervical Dystonia in Adult Participants
Recruiting·Ipsen logoIpsen·Phase 2·NCT06937931·132 enrolled
The Effects of Waning of Botulinum Toxin in the Treatment of Cervical Dystonia
Not yet recruiting·WWestern University, Canada·Phase 4·NCT06886750·45 enrolled
The Effect of Noninvasive Brain Stimulation on Symptoms of Cervical Dystonia
Not yet recruiting·FFondazione Policlinico Universitario Campus Bio-Medico·Preclinical·NCT07681284·26 enrolled
Efficacy and Safety of DYSPORT® Using 2mL Dilution in Adults With Cervical Dystonia.
Completed·Ipsen logoIpsen·Phase 3·NCT01753310·134 enrolled
A Study to Compare Dysport® and Botox® in the Treatment of Cervical Dystonia
Completed·SSeoul National University Hospital·Phase 4·NCT00950664·103 enrolled
Phase IV-Cervical Dystonia-INTEREST IN CD2
Completed·Ipsen logoIpsen·N/A·NCT01753349·1,050 enrolled
Study to Assess the Efficacy and Safety of Dysport® in Cervical Dystonia
Completed·Ipsen logoIpsen·Phase 3·NCT00447772·516 enrolled
Effects of Botulinum Toxin in Cervical Dystonia
Completed·HHenry Ford Health System·N/A·NCT01056861·7 enrolled
Daily Dystonia Practice - A Trial to Investigate NT 201, the Duration of Treatment Effect After One Injection Session and in Long-term Treatment in Cervical Dystonia
Completed·MMerz Pharmaceuticals GmbH·Phase 4·NCT00541905·82 enrolled
A Phase 2 Study to Evaluate the Safety and Efficacy of ABP-450 in the Treatment of Cervical Dystonia
Completed·AAEON Biopharma, Inc.·Phase 2·NCT04849988·61 enrolled
Long Term Safety And Effectiveness Of Dysport® In Adults With Cervical Dystonia
Completed·Ipsen logoIpsen·Phase 3·NCT01753336·112 enrolled
Study Comparing Short Term Efficacy of Dysport and Dysport NG to Placebo, and to Assess Efficacy and Safety of Dysport NG of Subjects With Cervical Dystonia
Completed·Ipsen logoIpsen·Phase 3·NCT01261611·382 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)