VivoSeq
Other

Chest Pain

25

Pipeline Programs↗

1

Active Trials↗

15

Companies Involved↗

Chest pain is an emerging landscape with 25 programs across 15 companies. The most active players are Menarini International Operations Luxembourg SA, Sanofi, Dexcel Pharma Technologies Ltd.. 13 therapies are approved with 3 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

49/100

Pipeline Velocity

0/100

Mech. Concentration

10/100

Completion Rate

76/100

Attrition Rate

20/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

M

Menarini International Operations Luxembourg SA

1 program

Phase 2Sanofi logo

Sanofi

1 program

Phase 3D

Dexcel Pharma Technologies Ltd.

1 program

Phase 3V

Viatris Specialty LLC

2 programs

ApprovedK

Kenvue Brands

1 program

ApprovedA

Averitas Pharma, Inc.

1 program

Approved

Pipeline

Programs by Phase

Analysis

Trial Status

25

clinical trials

Completed16 · 64%
Terminated3 · 12%
Unknown status3 · 12%
Withdrawn2 · 8%
Recruiting1 · 4%

Clinical Trials

Trial Activity

25 trials

Randomised Controlled Trial of Vericiguat in Patients With Coronary Microvascular Dysfunction Causing Stable Chest Pain (V-COM)
Recruiting·TThe University of Hong Kong·Preclinical·NCT06239974·94 enrolled
Efficacy of Gabapentin in the Treatment of Chest Pain and Paresthesia in Patients With Sternotomy
Completed·—·Phase 4·NCT00800527·110 enrolled
Chest Pain Perception and Capsaicin Sensitivity
Completed·BBassett Healthcare·N/A·NCT02346903·99 enrolled
Chest Pain Perception and Capsaicin Sensitivity in Patients With Acute Cardiac Ischemia
Completed·BBassett Healthcare·N/A·NCT02346916·22 enrolled
Stress CT Perfusion in Patients With Chest Pain
Completed·UUniversity of Chicago·N/A·NCT01969916·150 enrolled
Chest Pain Pilot Study
Completed·AstraZeneca logoAstraZeneca·Phase 3·NCT00251901·600 enrolled
Ranolazine for the Treatment of Chest Pain in HCM Patients
Completed·—·Phase 4·NCT01721967·14 enrolled
The Effects of Treatment With Sertraline for Noncardiac Chest Pain
Completed·MMaastricht University Medical Center·Phase 4·NCT01114100·210 enrolled
The Evaluation of Effectiveness Between Empirical and Guided Therapy for Unexplained Non-Cardiac Chest Pain
Completed·UUniversiti Sains Malaysia·Phase 2/3·NCT03319121·68 enrolled
Aggrastat to Zocor (AtoZ) - the Use of Two Approved Drugs to Treat Patients Who Have Experienced Chest Pain or a Heart Attack (0733-180)
Completed·—·Phase 3·NCT00251576·4,497 enrolled
The Effects of Cannabinoid on Patients With Non-GERD Related Non Cardiac Chest Pain
Completed·—·Phase 4·NCT01598207·13 enrolled
Treatment of Non-Cardiac Chest Pain With Imipramine or Cognitive-Behavioral Therapy
Completed·National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)·Phase 3·NCT00005575
Lidocaine 5% Patch (Lidoderm) for the Prevention of Acute and Chest Pain Following Robotic Valve Surgery
Completed·TThe Cleveland Clinic·N/A·NCT03120351·80 enrolled
Early Risk Stratification in ED Chest Pain Patients
Completed·—·N/A·NCT02364271·602 enrolled
Yinxingmihuan Oral Solution in Treatment of Chest Pain After PCI
Completed·CChina National Center for Cardiovascular Diseases·N/A·NCT06224582·320 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)