/
Other
Children
52
Pipeline Programs↗
44
Active Trials↗
68
Companies Involved↗
Children is a moderately active landscape with 52 programs across 68 companies. The most active players are Novo Nordisk, AOP Orphan Pharmaceuticals AG, Ultragenyx. 8 programs are in Phase 3.
Intelligence
Pipeline Metrics
Competitive Density
Pipeline Velocity
Mech. Concentration
Completion Rate
Attrition Rate
Competition
Competitive Landscape
Bubble size = clinical trials
Approved
Phase 3
Phase 2
Phase 1
Preclinical
Key Players
Top Companies Companies ranked by the number of pipeline programs they run for this disease.
Pipeline
Programs by Phase
Preclinical35
Phase 27
Phase 38
Approved
No programs
Analysis
Modality Breakdown
98%
Small molecule
40 of 41 classified programs — the dominant modality here.
Small molecule leads; the ring shows all 41 classified programs, each share of the total. Modality classified for 100% of 52 pipeline programs.
Analysis
Trial Status
555
clinical trials
Completed411 · 74%
Unknown status45 · 8%
Terminated32 · 6%
Recruiting25 · 5%
Withdrawn19 · 3%
Active, not recruiting11 · 2%
Other12 · 2%
Clinical Trials
Trial Activity
555 trials
Investigating the Pharmacokinetics of Tafenoquine in Healthy Papua New Guinean Children
Recruiting·—·Phase 4·NCT07052162·30 enrolled
CEUS for Blunt Abdominal Trauma in Children
Recruiting·—·Phase 4·NCT03490929·146 enrolled
Efficacy of INM004 in Children With STEC-HUS
Recruiting·—·Phase 3·NCT06389474·220 enrolled
Docosahexaenoic Acid on Breath Holding Spells in Children
Recruiting·—·Phase 3·NCT03965988·60 enrolled
Triheptanoin for Children With Primary-Specific Pyruvate Dehydrogenase Complex (PDC) Deficiency
Recruiting·—·Phase 1·NCT06340685·6 enrolled
Pharmacokinetics of Drugs Administered to Children
Recruiting·—·N/A·NCT03481881·200 enrolled
Dose Individualization of Antineoplastic Drugs and Anti-Infective Drug in Children With Hematoplastic Disease
Recruiting·—·Phase 4·NCT03844360·1,500 enrolled
Role of Coenzyme Q in ADHD in Children
Recruiting·—·Phase 3·NCT04216186·40 enrolled
Management of Children With Persistent ITP, A Novel Approach
Recruiting·—·N/A·NCT07068126·20 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)