VivoSeq
Neurology

Dementia

125

Pipeline Programs

41

Active Trials

47

Companies Involved

Dementia is a highly competitive landscape with 125 programs across 47 companies. The most active players are Teva, Avid Radiopharmaceuticals, Prism Pharmaceuticals. 30 therapies are approved with 27 more in late-stage development.

Pipeline Metrics

Competitive Density

75/100

Pipeline Velocity

41/100

Mech. Concentration

10/100

Completion Rate

81/100

Attrition Rate

13/100

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Programs by Phase

Modality Breakdown

95%

Small molecule

131 of 138 classified programs — the dominant modality here.

5%ALL OTHERSMonoclonal antibody32%Protein / enzyme32%Peptide1<1%

Small molecule leads; the ring shows all 138 classified programs, each share of the total. Modality classified for 100% of 139 pipeline programs.

Trial Status

188

clinical trials

Completed106 · 56%
Recruiting22 · 12%
Unknown status16 · 9%
Terminated16 · 9%
Withdrawn9 · 5%
Active, not recruiting9 · 5%
Other10 · 5%

Trial Activity

188 trials

Efficacy Biomarkers of DAOIB for Dementia
Recruiting··Phase 2·NCT05582161·123 enrolled
Novel Augmentation of DAOIB and Antioxidant for Early Dementia
Recruiting··Phase 2·NCT06467539·80 enrolled
Clinical Analgesic Management in Dementia
Recruiting·XXuanwu Hospital, Beijing·Phase 3·NCT07323914·10 enrolled
Rifaximin SSD in Dementia Trial
Recruiting··Phase 1/2·NCT06718686·20 enrolled
Page 1 of 13

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)