VivoSeq
Other

Edema

10

Pipeline Programs↗

2

Active Trials↗

12

Companies Involved↗

Edema is an early-stage landscape with 10 programs across 12 companies. The most active players are Merck & Co., Pfizer, Validus Pharmaceuticals. 7 therapies are approved.

Intelligence

Pipeline Metrics

Competitive Density

37/100

Pipeline Velocity

6/100

Mech. Concentration

20/100

Completion Rate

100/100

Attrition Rate

0/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Merck & Co. logo

Merck & Co.

1 program

Phase 2Pfizer logo

Pfizer

2 programs

ApprovedV

Validus Pharmaceuticals

1 program

ApprovedC

Chattem

1 program

ApprovedAlnylam Pharmaceuticals logo

Alnylam Pharmaceuticals

1 program

ApprovedM

Milestone Pharmaceuticals Inc.

1 program

Approved

Pipeline

Programs by Phase

Analysis

Modality Breakdown

82%

Small molecule

9 of 11 classified programs — the dominant modality here.

18%ALL OTHERSMonoclonal antibody19%Protein / enzyme19%

Small molecule leads; the ring shows all 11 classified programs, each share of the total. Modality classified for 100% of 11 pipeline programs.

Analysis

Trial Status

10

clinical trials

Completed8 · 80%
Not yet recruiting1 · 10%
Active, not recruiting1 · 10%

Clinical Trials

Trial Activity

10 trials

A Phase II Study of Anti-PD-1 (MK-3475) Therapy in Patients With Metastatic Inflammatory Breast Cancer (IBC) or Non-IBC Triple Negative Breast Cancer (TNBC) Who Have Achieved Clinical Response or Stable Disease to Prior Chemotherapy
Active, not recruiting·MM.D. Anderson Cancer Center·Phase 2·NCT02411656·71 enrolled
Anticholinergics for Cervical Edema in Labor
Not yet recruiting·TThe University of Texas Health Science Center, Houston·Phase 2/3·NCT06702670·200 enrolled
Manage Macular Cystoid Edema With Retinal Vein Obstruction Using Traditional Chinese Medicine and Ranibizumab
Completed·—·Phase 4·NCT06234514·111 enrolled
Effects of Cold Application and Heparinoid on Periorbital Edema and Ecchymosis
Completed·NNecmettin Erbakan University·N/A·NCT04119297·90 enrolled
Role of Acetazolamide and Hydrochlorothiazide Followed by Furosemide in Treating Nephrotic Edema
Completed·SShiraz University of Medical Sciences·Phase 4·NCT02427880·20 enrolled
Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema
Completed·HHacettepe University·Phase 4·NCT05466604·60 enrolled
Long-Term Study of EN3835 (CCH-aaes) in Edematous Fibrosclerotic Panniculopathy (Cellulite)
Completed·Endo Pharmaceuticals logoEndo Pharmaceuticals·Phase 3·NCT03526549·483 enrolled
A Study to Investigate Pharmacodynamics and Pharmacokinetics of OPC-41061 in Patients With Hepatic Edema
Completed·Otsuka logoOtsuka·Phase 3·NCT01114828·40 enrolled
A Pharmacovigilance Study of Brain Oedema
Completed·UUniversity of Peshawar·N/A·NCT04311359·9,524 enrolled
Handheld vs Mechanically-assisted Scanning of Fascial Edema Following Impacted Third Molar Surgery
Completed·EEge University·N/A·NCT07690488·20 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)