VivoSeq
Other

Head Injury

16

Pipeline Programs↗

1

Active Trials↗

12

Companies Involved↗

Head Injury is an emerging landscape with 16 programs across 12 companies. The most active players are Tenax Therapeutics, Inc., NeuroVive Pharmaceutical AB, Abela Pharmaceuticals, Inc.. 2 therapies are approved with 2 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

43/100

Pipeline Velocity

0/100

Mech. Concentration

50/100

Completion Rate

89/100

Attrition Rate

7/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

T

Tenax Therapeutics, Inc.

1 program

Phase 2N

NeuroVive Pharmaceutical AB

1 program

Phase 2A

Abela Pharmaceuticals, Inc.

1 program

Phase 2AstraZeneca logo

AstraZeneca

1 program

Phase 2A

Amring

1 program

Phase 3F

Fresenius

1 program

Phase 3

Pipeline

Programs by Phase

Analysis

Trial Status

14

clinical trials

Completed8 · 57%
Unknown status4 · 29%
Recruiting1 · 7%
Terminated1 · 7%

Clinical Trials

Trial Activity

14 trials

Clinical Randomisation of an Anti-fibrinolytic in Symptomatic Mild Head Injury in Older Adults
Recruiting·LLondon School of Hygiene and Tropical Medicine·Phase 3·NCT04521881·5,000 enrolled
Valproate for Mood Swings and Alcohol Use Following Head Injury
Completed·UUniversity of Colorado, Denver·N/A·NCT01760785·50 enrolled
Clinical Randomisation of an Antifibrinolytic in Significant Head Injury
Completed·LLondon School of Hygiene and Tropical Medicine·Phase 3·NCT01402882·12,737 enrolled
Mild Head Injury, Antiplatelets, and Anticoagulants
Completed·FFondazione Policlinico Universitario Agostino Gemelli IRCCS·N/A·NCT04741334·2,127 enrolled
Copenhagen Head Injury Ciclosporin (CHIC) Study
Completed·NNeuroVive Pharmaceutical AB·Phase 2·NCT01825044·16 enrolled
Could Early Atorvastatin Offer Anti Inflammatory Effects Upon Brain in Traumatic Head Injury?
Completed·—·N/A·NCT04718155·30 enrolled
The Toronto Prehospital Hypertonic Resuscitation Head Injury and Multi Organ Dysfunction Trial (TOPHR HIT)
Completed·SSunnybrook Health Sciences Centre·Phase 3·NCT01642524·114 enrolled
Effect of Rosuvastatin on Amnesia and Orientation Through Galveston Outcome Amnesia Test in Moderate Head Injury
Completed·UUniversidad Autonoma de San Luis Potosí·Phase 2·NCT00329758·20 enrolled
Dynamic Vision Testing and Concussion Management
Completed·California State University, Northridge·N/A·NCT04837066·100 enrolled
Study of Oxycyte in Severe Closed Head Injury
Terminated·TTenax Therapeutics, Inc.·Phase 2·NCT00174980·9 enrolled
Divalproex Sodium for Mood Swings and Alcohol Use Following Head Injury.
Unknown status·—·N/A·NCT01326663·50 enrolled
Study of the Approximate Entropy of Adrenocorticotropic Hormone and Cortisol Secretion in Patients With Head Injury
Unknown status·NNational Center for Research Resources (NCRR)·N/A·NCT00006270·32 enrolled
Controlled Trial of ABELADRUG200 in Closed, Severe Head Injury
Unknown status·AAbela Pharmaceuticals, Inc.·Phase 1/2·NCT00810940·30 enrolled
High Dose Hyperoncotic Serum Albumin for the Treatment of the Acute Phase of Severe Head Injury
Unknown status·UUniversity Hospital, Angers·Phase 2/3·NCT00152685·40 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)