Gastroenterology
Hemorrhoid
50
Pipeline Programs↗
14
Active Trials↗
20
Companies Involved↗
Hemorrhoid is a moderately active landscape with 50 programs across 20 companies. The most active players are Citius Pharmaceuticals, Inc., Nivagen Pharmaceuticals Inc., Revance Therapeutics, Inc.. 22 therapies are approved with 7 more in late-stage development.
Intelligence
Pipeline Metrics
Competitive Density
Pipeline Velocity
Mech. Concentration
Completion Rate
Attrition Rate
Competition
Competitive Landscape
Bubble size = clinical trials
Approved
Phase 3
Phase 2
Phase 1
Preclinical
Key Players
Top Companies Companies ranked by the number of pipeline programs they run for this disease.
Pipeline
Programs by Phase
Preclinical14
Phase 26
Phase 37
Analysis
Trial Status
58
clinical trials
Completed31 · 53%
Unknown status10 · 17%
Recruiting6 · 10%
Not yet recruiting5 · 9%
Terminated2 · 3%
Enrolling by invitation2 · 3%
Other2 · 3%
Clinical Trials
Trial Activity
58 trials
Topical Nifedipine 0.3% Plus Lidocaine 1.5% for Uncomplicated Hemorrhoidal Disease
Recruiting·—·N/A·NCT07295886·80 enrolled
The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Hemorrhoid Surgery
Recruiting·—·N/A·NCT07442539·156 enrolled
Efficacy and Safety Evaluation of Ruscus Aculeatus L in Patients With Hemorrhoids
Recruiting·SSultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey·Phase 4·NCT07128979·250 enrolled
Botulinum Toxin A Before Hemorrhoidectomy to Prevent Postoperative Pain
Recruiting·LLomonosov Moscow State University Medical Research and Educational Center·Phase 2·NCT07399860·292 enrolled
The Efficacy of Aescin in Combination With MPFF in the Early Control of Bleeding From Acute Internal Hemorrhoids, A Randomized Controlled Trial
Not yet recruiting·—·N/A·NCT06363513·60 enrolled
Nitroglycerin Ointment for Pain Relief After Endoscopic Hemorrhoid Band Ligation
Not yet recruiting·—·Phase 4·NCT07391501·68 enrolled
Bleeding Reduction in Grade II-III Haemorrhoids Through Embolization Treatment
Not yet recruiting·CCardiovascular and Interventional Radiological Society of Europe·N/A·NCT07264413·250 enrolled
Quadruple-Blind, Placebo-Controlled, Parallel-Group Randomized Controlled Trial to Evaluate the Efficacy and Safety of Nimsai Herbal in Patients With Grade 2-3 Hemorrhoids
Not yet recruiting·—·Phase 3·NCT07669662·50 enrolled
The Efficacy of Aescin in Combination With Micronized Purified Flavonoid Fraction (MPFF) in the Control of Bleeding and Prevent Recurrence of Acute Internal Hemorrhoids, A Randomized Controlled Trial, A Pilot Study
Enrolling by invitation·—·Phase 1·NCT06748014·120 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)